Evidence map›Paper›PMID 34205940›Full record

ArticleViruses2021

DIC-Like Syndrome Following Administration of ChAdOx1 nCov-19 Vaccination.

Gerardo Casucci, Domenico Acanfora

Open access · goldAbstract readCase Reports
In one paragraph

Article in Viruses, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Post-SARS-CoV-2 vaccination venous sinus thrombosis: a literature review of 308 cases.The Egyptian journal of neurology, psychiatry and neurosurgery · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Gerardo CasucciUnit of Internal Medicine, San Francesco Hospital, Viale Europa 21, 82037 Telese Terme, Italy.
Domenico AcanforaUnit of Internal Medicine, San Francesco Hospital, Viale Europa 21, 82037 Telese Terme, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In recent weeks, adverse reactions have been reported after administration of Oxford-AstraZeneca chimpanzee adenovirus vectored vaccine ChAdOx1 nCoV-19 (AZD1222), in particular thrombus formation, which has led several European Countries to discontinue administration of this vaccine. On March 8, 2021, the European Medicines Agency Safety Committee did not confirm this probable association. We report the case of a patient who developed disseminated intravascular coagulation after the first dose of Oxford-Astra Zeneca vaccine, which resolved in a few days with the administration of dexamethasone and enoxaparin. This work demonstrates the safety of the Oxford-Astra Zeneca vaccine and that any development of side effects can be easily managed with a prompt diagnosis and in a short time with a few commonly used drugs.

Indexed as

ChAdOx1 nCoV-19Clinical Laboratory TechniquesCOVID-19COVID-19 VaccinesDexamethasoneDisseminated Intravascular CoagulationEnoxaparinFemaleHumansMiddle AgedSARS-CoV-2VaccinationChAdOx1 nCoV-19COVID-19 VaccinesDexamethasoneEnoxaparinchimpanzee adenovirus vectored vaccinedisseminated intravascular coagulationSARS-CoV-2

Identifiers

PMID34205940
PMCPMC8226681
OpenAlexW3168170334

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.