Evidence map›Paper›PMID 34205929›Full record

ArticleGenes2021

T Cell Receptor Genotype and

John P Mordes, Laura Cort, Zhijun Liu, Ryan Eberwine, Elizabeth P Blankenhorn, Brian G Pierce

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Genes, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.4field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Deletion of Vβ3Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  5. Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

John P MordesDepartment of Medicine, University of Massachusetts Medical School, Worcester, MA 01655, USA.
Laura CortDepartment of Microbiology and Immunology, Center for Immunogenetics and Inflammatory Diseases, Drexel University College of Medicine, Philadelphia, PA 19129, USA.ORCID 0000-0003-2086-0094
Zhijun LiuDepartment of Medicine, University of Massachusetts Medical School, Worcester, MA 01655, USA.ORCID 0000-0003-2323-462X
Ryan EberwineDepartment of Microbiology and Immunology, Center for Immunogenetics and Inflammatory Diseases, Drexel University College of Medicine, Philadelphia, PA 19129, USA.
Elizabeth P BlankenhornDepartment of Microbiology and Immunology, Center for Immunogenetics and Inflammatory Diseases, Drexel University College of Medicine, Philadelphia, PA 19129, USA.
Brian G PierceInstitute for Bioscience and Biotechnology Research, University of Maryland, Rockville, MD 20850, USA.
Drexel University · USUniversity of Massachusetts Chan Medical School · USUniversity of Maryland, Baltimore · US

Funding

High Resolution Modeling and Design of T-Cell ReceptorsR01GM126299 · NIGMS · UNIV OF MARYLAND, COLLEGE PARK · PI PIERCE, BRIAN G. · 2018 to 2021
$1.3M
NIGMS NIH HHS R01 GM126299NIH HHS AI088480
6 · The paper itself

Abstract

Genetic analyses of human type 1 diabetes (T1D) have yet to reveal a complete pathophysiologic mechanism. Inbred rats with a high-risk class II major histocompatibility complex (MHC) haplotype (RT1B/D

Indexed as

AnimalsAutoimmunityDiabetes Mellitus, Type 1GenotypeHistocompatibility Antigens Class IIInsulinPeptide FragmentsProtein BindingRatsRats, Inbred LewReceptors, Antigen, T-Cell, alpha-betaHistocompatibility Antigens Class IIInsulininsulin B (9-23)Peptide FragmentsReceptors, Antigen, T-Cell, alpha-betaautoimmunitygeneticsimmunogeneticsMHCratTCRtype 1 diabetes

Identifiers

PMID34205929
PMCPMC8227067
OpenAlexW3167645067

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.