Evidence map›Paper›PMID 34205928›Full record

ReviewJournal of clinical medicine2021

Post-COVID-19 Pulmonary Fibrosis: Novel Sequelae of the Current Pandemic.

Shiva Rattan Ambardar, Stephanie L Hightower, Nikhil A Huprikar, Kevin K Chung, Anju Singhal, Jacob F Collen

Open access · goldAbstract readReview
In one paragraph

Review in Journal of clinical medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 70 papers.

0numbers the graph read from it
0cells of the map it votes in
70citing papers in PubMed
15.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

70 citing papers in PubMed, 116 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Review
  5. Article
  6. Review
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Review
  13. Effect of Home-Based Pulmonary Rehabilitation on Pulmonary Fibrosis.Multidisciplinary respiratory medicine · 2024
    Article
  14. Article
  15. Review
  16. Review
  17. Article
  18. ACE2: the node connecting the lung cancer and COVID-19.American journal of cancer research · 2024
    Review
  19. Review
  20. Balancing the value and risk of exercise-based therapy post-COVID-19: a narrative review.European respiratory review : an official journal of the European Respiratory Society · 2023
    Review

10 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Shiva Rattan AmbardarDepartment of Medicine, F. Edward Hebert School of Medicine, Uniformed Services University of the Health Sciences, Bethesda, MD 20814, USA.
Stephanie L HightowerDepartment of Medicine, F. Edward Hebert School of Medicine, Uniformed Services University of the Health Sciences, Bethesda, MD 20814, USA.
Nikhil A HuprikarDepartment of Medicine, F. Edward Hebert School of Medicine, Uniformed Services University of the Health Sciences, Bethesda, MD 20814, USA.
Kevin K ChungDepartment of Medicine, F. Edward Hebert School of Medicine, Uniformed Services University of the Health Sciences, Bethesda, MD 20814, USA.ORCID 0000-0002-2781-3787
Anju SinghalInova Fairfax Advanced Lung Disease Center, Fairfax, VA 22033, USA.
Jacob F CollenDepartment of Medicine, F. Edward Hebert School of Medicine, Uniformed Services University of the Health Sciences, Bethesda, MD 20814, USA.
Uniformed Services University of the Health Sciences · USInova Fairfax Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Since the initial identification of the novel coronavirus SARS-CoV-2 in December 2019, the COVID-19 pandemic has become a leading cause of morbidity and mortality worldwide. As effective vaccines and treatments begin to emerge, it will become increasingly important to identify and proactively manage the long-term respiratory complications of severe disease. The patterns of imaging abnormalities coupled with data from prior coronavirus outbreaks suggest that patients with severe COVID-19 pneumonia are likely at an increased risk of progression to interstitial lung disease (ILD) and chronic pulmonary vascular disease. In this paper, we briefly review the definition, classification, and underlying pathophysiology of interstitial lung disease (ILD). We then review the current literature on the proposed mechanisms of lung injury in severe COVID-19 infection, and outline potential viral- and immune-mediated processes implicated in the development of post-COVID-19 pulmonary fibrosis (PCPF). Finally, we address patient-specific and iatrogenic risk factors that could lead to PCPF and discuss strategies for reducing risk of pulmonary complications/sequelae.

Indexed as

ARDScoronavirusCOVID-19interstitial lung diseasemechanical ventilationpneumoniapulmonary fibrosisSARS-CoV-2venous thromboembolism

Identifiers

PMID34205928
PMCPMC8199255
OpenAlexW3170467002

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.