Evidence map›Paper›PMID 34205780›Full record

ArticlePharmaceutics2021

Imaging-Based Characterization of a

Solène Marie, Irene Hernández-Lozano, Louise Breuil, Charles Truillet, Shuiying Hu, Alex Sparreboom, Nicolas Tournier, Oliver Langer

Open access · goldAbstract read
In one paragraph

Article in Pharmaceutics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Pharmacokinetic Imaging UsingPharmaceuticals (Basel, Switzerland) · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 3 countries.

Solène MarieLaboratoire d'Imagerie Biomédicale Multimodale, BIOMAPS, Service Hospitalier Frédéric Joliot, Université Paris-Saclay, CEA, CNRS, Inserm, 4 Place du Général Leclerc, 91401 Orsay, France.ORCID 0000-0001-5247-4871
Irene Hernández-LozanoDepartment of Clinical Pharmacology, Medical University of Vienna, 1090 Vienna, Austria.ORCID 0000-0002-3700-7690
Louise BreuilLaboratoire d'Imagerie Biomédicale Multimodale, BIOMAPS, Service Hospitalier Frédéric Joliot, Université Paris-Saclay, CEA, CNRS, Inserm, 4 Place du Général Leclerc, 91401 Orsay, France.
Charles TruilletLaboratoire d'Imagerie Biomédicale Multimodale, BIOMAPS, Service Hospitalier Frédéric Joliot, Université Paris-Saclay, CEA, CNRS, Inserm, 4 Place du Général Leclerc, 91401 Orsay, France.
Shuiying HuDivision of Pharmaceutics and Pharmacology, College of Pharmacy, The Ohio State University, Columbus, OH 43210, USA.ORCID 0000-0002-9806-7734
Alex SparreboomDivision of Pharmaceutics and Pharmacology, College of Pharmacy, The Ohio State University, Columbus, OH 43210, USA.
Nicolas TournierLaboratoire d'Imagerie Biomédicale Multimodale, BIOMAPS, Service Hospitalier Frédéric Joliot, Université Paris-Saclay, CEA, CNRS, Inserm, 4 Place du Général Leclerc, 91401 Orsay, France.ORCID 0000-0002-0755-2030
Oliver LangerDepartment of Clinical Pharmacology, Medical University of Vienna, 1090 Vienna, Austria.
Centre National de la Recherche Scientifique · FRMedical University of Vienna · ATThe Ohio State University · US

Funding

Prevention of paclitaxel-induced peripheral neuropathy with nilotinibR01CA238946 · NCI · OHIO STATE UNIVERSITY · PI HU, SHUIYING, LUSTBERG, MARYAM B. · 2019 to 2023
$2.9M
Agence nationale de la recherche ANR-11-INBS-0006Austrian Science Fund KLI 694-B30Austrian Science Fund FWF KLI 694NCI NIH HHS R01 CA238946
6 · The paper itself

Abstract

Organic anion-transporting polypeptide 2B1 (OATP2B1) is co-localized with OATP1B1 and OATP1B3 in the basolateral hepatocyte membrane, where it is thought to contribute to the hepatic uptake of drugs. We characterized a novel

Indexed as

[11C]erlotinib[99mTc]mebrofenindrug transportersimagingliverOATP2B1pharmacokinetic modeling

Identifiers

PMID34205780
PMCPMC8233734
OpenAlexW3174268430

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.