ReviewHealthcare (Basel, Switzerland)2021
Review of Pharmacotherapy for Tinnitus.
Review in Healthcare (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 1 synthesis or guideline pooled it, 37 citations in OpenAlex.
- Pharmacotherapy options for the management of subjective tinnitus: a systematic review and network meta-analysis.BMJ open · 2025Pooled it
- An open-label, proof-of-mechanism trial evaluating a neuroactive steroid GABA modulator in tinnitus.Frontiers in neurology · 2025Trial
- Hemodynamic Changes Following Acupuncture and Moxibustion in Patients with Subjective Tinnitus: An Acceleration Photoplethysmography and Pulsed-Wave Doppler Ultrasound Study.Audiology research · 2026Article
- Disproportionality analysis of drug-associated tinnitus safety signals: a 43-year pharmacovigilance study.Naunyn-Schmiedeberg's archives of pharmacology · 2026Article
- Repurposing Renin-Angiotensin System Drugs for the Treatment of Audiovestibular Disorders.Journal of clinical medicine · 2026Review
- Mindfulness-based therapy for chronic tinnitus: a narrative review.Frontiers in psychology · 2026Review
- Assessment of Treatment Efficacy in Patients with Chronic Tinnitus: An Ambispective Cohort Study.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2025Article
- A Clinical Evaluation of Calcium and Fluoride Supplementation for Tinnitus in Non-Surgical Otosclerosis: Insights from a Tertiary Care Center in Romania.Medicina (Kaunas, Lithuania) · 2025Article
- Neuroplasticity and tinnitus: the role of Brain-Derived Neurotrophic Factor in pathogenesis and treatment.Frontiers in neuroscience · 2025Review
- Article
- Iron deficiency anemia and the risk of new-onset tinnitus in female patients: a cohort study.Frontiers in nutrition · 2025Article
- Unravelling the Silence: Exploring Tinnitus Pathophysiology and the Promise of Traditional Chinese Medicine.International journal of general medicine · 2025Review
- [Diagnosis and treatment of middle ear myoclonic tinnitus].Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology head and neck surgery · 2024Review
- Tinnitus Prevalence, Associated Characteristics, and Treatment Patterns among Adults in Saudi Arabia.Audiology research · 2024Article
- Exploring the interplay of depression, sleep quality, and hearing in tinnitus-related handicap: insights from polysomnography and pure-tone audiometry.BMC psychiatry · 2024Article
- Repeated Bilateral Transcranial Direct Current Stimulation over Auditory Cortex for Tinnitus Treatment: A Double-Blinded Randomized Controlled Clinical Trial.Brain sciences · 2024Article
- The impact of tinnitus on Dutch general practices: A retrospective study using routine healthcare data.PloS one · 2024Article
- The effect of MemoVigor 2 on recent-onset idiopathic tinnitus: a randomized double-blind placebo-controlled clinical trial.Frontiers in pharmacology · 2024Article
- The Effect of Anxiolytics on Tinnitus.Journal of clinical medicine · 2023Article
- Efficacy and Safety of Co-Administered St. John's Wort andJournal of clinical medicine · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Various medications are currently used in the treatment of tinnitus, including anesthetics, antiarrhythmics, anticonvulsants, antidepressants, antihistamines, antipsychotics, anxiolytics, calcium channel blockers, cholinergic antagonists, NMDA antagonists, muscle relaxants, vasodilators, and vitamins. To date, however, no medications have been specifically approved to treat tinnitus by the US Food and Drug Administration (FDA). In addition, medicines used to treat other diseases, as well as foods and other ingested materials, can result in unwanted tinnitus. These include alcohol, antineoplastic chemotherapeutic agents and heavy metals, antimetabolites, antitumor agents, antibiotics, caffeine, cocaine, marijuana, nonnarcotic analgesics and antipyretics, ototoxic antibiotics and diuretics, oral contraceptives, quinine and chloroquine, and salicylates. This review, therefore, describes the medications currently used to treat tinnitus, including their mechanisms of action, therapeutic effects, dosages, and side-effects. In addition, this review describes the medications, foods, and other ingested agents that can induce unwanted tinnitus, as well as their mechanisms of action.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.