Evidence map›Paper›PMID 34205768›Full record

ArticleMolecules (Basel, Switzerland)2021

Targeting 3CLpro and SARS-CoV-2 RdRp by

Nourhan Hisham Shady, Alaa M Hayallah, Mamdouh F A Mohamed, Mohammed M Ghoneim, Garri Chilingaryan, Mohammad M Al-Sanea, Mostafa A Fouad, Mohamed Salah Kamel, Usama Ramadan Abdelmohsen

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Wound Healing and Antioxidant Capabilities ofPlants (Basel, Switzerland) · 2022
    Article
  5. An overview of potential inhibitors targeting non-structural proteins 3 (PLComputational and structural biotechnology journal · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Nourhan Hisham ShadyDepartment of Pharmacognosy, Faculty of Pharmacy, Deraya University, Universities Zone, New Minia City 61111, Egypt.
Alaa M HayallahDepartment of Pharmaceutical Organic Chemistry, Faculty of Pharmacy, Assiut University, Assiut 71526, Egypt.ORCID 0000-0001-9517-8650
Mamdouh F A MohamedDepartment of Pharmaceutical Chemistry, Faculty of Pharmacy, Sohag University, Sohag 82524, Egypt.ORCID 0000-0002-7046-1799
Mohammed M GhoneimDepartment of Pharmacy Practice, College of Pharmacy, AlMaarefa University, Ad Diriyah 13713, Saudi Arabia.ORCID 0000-0002-9179-4373
Garri ChilingaryanInstitute of Molecular Biology of NAS RA, Yerevan 0014, Armenia.ORCID 0000-0001-7367-7678
Mohammad M Al-SaneaDepartment of Pharmaceutical Chemistry, College of Pharmacy, Jouf University, Aljouf 72341, Saudi Arabia.ORCID 0000-0002-9820-4022
Mostafa A FouadDepartment of Pharmacognosy, Faculty of Pharmacy, Minia University, Minia 61519, Egypt.
Mohamed Salah KamelDepartment of Pharmacognosy, Faculty of Pharmacy, Deraya University, Universities Zone, New Minia City 61111, Egypt.
Usama Ramadan AbdelmohsenDepartment of Pharmacognosy, Faculty of Pharmacy, Deraya University, Universities Zone, New Minia City 61111, Egypt.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Since December 2019, novel coronavirus disease 2019 (COVID-19) pandemic has caused tremendous economic loss and serious health problems worldwide. In this study, we investigated 14 natural compounds isolated from

Indexed as

Amino SugarsAnimalsAntiviral AgentsBinding SitesBiological ProductsComputational BiologyCoronavirus 3C ProteasesCOVID-19 Drug TreatmentHumansLigandsModels, MolecularMolecular Docking SimulationMolecular Dynamics SimulationPoriferaProtease InhibitorsPyridinesAmino Sugarsamphimedoside CAntiviral AgentsBiological ProductsCoronavirus 3C ProteasesLigandsnakinadine BProtease InhibitorsPyridinesRNA-Dependent RNA PolymeraseAmphimedon sp.coronavirusCOVID-19molecular dockingsponge

Identifiers

PMID34205768
PMCPMC8235472

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.