Evidence map›Paper›PMID 34205710›Full record

ReviewInternational journal of molecular sciences2021

The Role of Neuropeptide B and Its Receptors in Controlling Appetite, Metabolism, and Energy Homeostasis.

Tatiana Wojciechowicz, Maria Billert, Mariami Jasaszwili, Mathias Z Strowski, Krzysztof W Nowak, Marek Skrzypski

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Tatiana WojciechowiczDepartment of Animal Physiology, Biochemistry and Biostructure, Poznań University of Life Sciences, 35 Wołyńska St, 60-637 Poznań, Poland.ORCID 0000-0002-3651-0972
Maria BillertDepartment of Animal Physiology, Biochemistry and Biostructure, Poznań University of Life Sciences, 35 Wołyńska St, 60-637 Poznań, Poland.ORCID 0000-0002-2198-6046
Mariami JasaszwiliDepartment of Animal Physiology, Biochemistry and Biostructure, Poznań University of Life Sciences, 35 Wołyńska St, 60-637 Poznań, Poland.ORCID 0000-0002-2821-5076
Mathias Z StrowskiDepartment of Hepatology and Gastroenterology, Charité-University Medicine Berlin, D-13353 Berlin, Germany.ORCID 0000-0001-7160-0407
Krzysztof W NowakDepartment of Animal Physiology, Biochemistry and Biostructure, Poznań University of Life Sciences, 35 Wołyńska St, 60-637 Poznań, Poland.ORCID 0000-0002-1948-6544
Marek SkrzypskiDepartment of Animal Physiology, Biochemistry and Biostructure, Poznań University of Life Sciences, 35 Wołyńska St, 60-637 Poznań, Poland.ORCID 0000-0003-4059-1362
University of Life Sciences in Poznań · PLPark-Klinik Weißensee · DE

Funding

Narodowe Centrum Nauki 2016/21/B/NZ9/00943the Faculty of Veterinary Medicine and Animal Science Poznan University of Life Sciences financed by the Polish Ministry of Science and Higher Education 506.558.09.00, 506.558.04.00 and 506.558.05.00
6 · The paper itself

Abstract

Neuropeptide B (NPB) is a peptide hormone that was initially described in 2002. In humans, the biological effects of NPB depend on the activation of two G protein-coupled receptors, NPBWR1 (GPR7) and NPBWR2 (GPR8), and, in rodents, NPBWR1. NPB and its receptors are expressed in the central nervous system (CNS) and in peripheral tissues. NPB is also present in the circulation. In the CNS, NPB modulates appetite, reproduction, pain, anxiety, and emotions. In the peripheral tissues, NPB controls secretion of adrenal hormones, pancreatic beta cells, and various functions of adipose tissue. Experimental downregulation of either NPB or NPBWR1 leads to adiposity. Here, we review the literature with regard to NPB-dependent control of metabolism and energy homeostasis.

Indexed as

Energy MetabolismAnimalsAppetiteBrainGlucoseHomeostasisHumansLipid MetabolismNeuropeptidesReproductionGlucoseneuropeptide BNeuropeptidesappetiteenergy homeostasismetabolismneuropeptide BNPBWR1NPRBWR2

Identifiers

PMID34205710
PMCPMC8234850
OpenAlexW3175761687

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.