ReviewJournal of clinical medicine2021
Incidence of Fat Embolism Syndrome in Femur Fractures and Its Associated Risk Factors over Time-A Systematic Review.
Review in Journal of clinical medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
30 citing papers in PubMed, 1 synthesis or guideline pooled it, 45 citations in OpenAlex.
- Complications associated using the reamer-irrigator -aspirator (RIA) system: a systematic review and meta-analysis.Archives of orthopaedic and trauma surgery · 2023Pooled it
- Article
- Incidence, mortality, and factors associated with fat embolism syndrome in patients with long bone fractures at a trauma referral center in Bogotá, Colombia: 2016-2019 and 2022-2023.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2026Article
- Complications after intramedullary nailing of diaphyseal femur fractures in a level I trauma center in Finland.OTA international : the open access journal of orthopaedic trauma · 2026Article
- Neurologically predominant fat embolism syndrome in an octogenarian with dementia: diagnostic challenges and prolonged recovery.BMC neurology · 2026Article
- Sudden Cardiac Arrest in Proximal Femur Fracture: The Role of Admission Blood Parameters.Cureus · 2026Article
- Fat embolism syndrome following severe blunt chest trauma treated with veno-venous extracorporeal membrane oxygenation: A case report.Trauma case reports · 2025Article
- Fat embolism syndrome caused by fracture or liposuction: a retrospective case series of nine patients.Annals of medicine · 2025Article
- Review
- Open fractures associated with earthquakes and high-energy trauma: Clinical outcomes and management strategies.Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES · 2025Article
- Article
- Assessing Cardiopulmonary Safety of Intramedullary Bone Graft Harvesting: A Comparative Study of the RIA 2 System and the ARA Concept.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2025Article
- Atypical presentation of fat embolism syndrome: A case report.Trauma case reports · 2025Article
- Percutaneous thrombectomy of fat embolism in-transit.Journal of vascular surgery cases and innovative techniques · 2025Article
- Intraoperative Management of Hypoxemia with Anticoagulant-Free Venovenous Extracorporeal Membrane Oxygenation Amid Diagnostic Uncertainty.Annals of cardiac anaesthesia · 2025Article
- Irrigation of the intramedullary channel improves outcome of DAIR in a sheep model.NPJ biofilms and microbiomes · 2025Article
- Extracorporeal Membrane Oxygenation Use in Fat Embolism Syndrome: Current Perspectives and Clinical Insights (A 20-Year Review).Journal of clinical medicine · 2025Review
- Fat embolism syndrome following femoral shaft fracture: A case report and diagnostic considerations.Radiology case reports · 2025Article
- By activating endothelium histone H4 mediates oleic acid-induced acute respiratory distress syndrome.BMC pulmonary medicine · 2025Article
- Profoundly Delayed Emergence due to Pulmonary Embolism.Case reports in anesthesiology · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundFat embolism (FE) continues to be mentioned as a substantial complication following acute femur fractures. The aim of this systematic review was to test the hypotheses that the incidence of fat embolism syndrome (FES) has decreased since its description and that specific injury patterns predispose to its development. MATERIALS AND
methodsData Sources: MEDLINE, Embase, PubMed, and Cochrane Central Register of Controlled Trials databases were searched for articles from 1 January 1960 to 31 December 2019. STUDY SELECTION: Original articles that provide information on the rate of FES, associated femoral injury patterns, and therapeutic and diagnostic recommendations were included. DATA EXTRACTION: Two authors independently extracted data using a predesigned form. STATISTICS: Three different periods were separated based on the diagnostic and treatment changes: Group 1: 1 January 1960-12 December 1979, Group 2: 1 January 1980-1 December 1999, and Group 3: 1 January 2000-31 December 2019, chi-square test, χ
resultsFifteen articles were included (
conclusionsThere has been a significant decrease in the incidence of FES over time. The injury pattern impacts the frequency of FES. The diagnostic and therapeutic approach to FES remains highly heterogenic to this day.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.