Evidence map›Paper›PMID 34205654›Full record

ArticleCancers2021

B-Helper Neutrophils in Regional Lymph Nodes Correlate with Improved Prognosis in Patients with Head and Neck Cancer.

Ekaterina Pylaeva, Irem Ozel, Anthony Squire, Ilona Spyra, Charlotte Wallner, Magdalena Korek, Georg Korschunow, Maksim Domnich, Elena Siakaeva, Moritz Goetz and 4 more

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.5field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
  2. Article
  3. Harnessing myeloid cells in cancer.Molecular cancer · 2025
    Review
  4. Review
  5. Article
  6. Article
  7. 8-Gene signature related to CD8Frontiers in genetics · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 2 institutions in 1 country.

Ekaterina PylaevaDepartment of Otorhinolaryngology, University Hospital Essen, University Duisburg-Essen, 45147 Essen, Germany.ORCID 0000-0002-3941-9664
Irem OzelDepartment of Otorhinolaryngology, University Hospital Essen, University Duisburg-Essen, 45147 Essen, Germany.ORCID 0000-0002-7007-9928
Anthony SquireInstitute of Experimental Immunology and Imaging, University Hospital Essen, University Duisburg-Essen, 45141 Essen, Germany.
Ilona SpyraDepartment of Otorhinolaryngology, University Hospital Essen, University Duisburg-Essen, 45147 Essen, Germany.
Charlotte WallnerDepartment of Otorhinolaryngology, University Hospital Essen, University Duisburg-Essen, 45147 Essen, Germany.
Magdalena KorekDepartment of Otorhinolaryngology, University Hospital Essen, University Duisburg-Essen, 45147 Essen, Germany.
Georg KorschunowDepartment of Otorhinolaryngology, University Hospital Essen, University Duisburg-Essen, 45147 Essen, Germany.
Maksim DomnichDepartment of Otorhinolaryngology, University Hospital Essen, University Duisburg-Essen, 45147 Essen, Germany.ORCID 0000-0003-4954-5418
Elena SiakaevaDepartment of Otorhinolaryngology, University Hospital Essen, University Duisburg-Essen, 45147 Essen, Germany.
Moritz GoetzInstitute of Pathology, University Hospital Essen, University of Duisburg-Essen, 45147 Essen, Germany.
Agnes BankfalviInstitute of Pathology, University Hospital Essen, University of Duisburg-Essen, 45147 Essen, Germany.
Stephan LangDepartment of Otorhinolaryngology, University Hospital Essen, University Duisburg-Essen, 45147 Essen, Germany.
Benjamin KansyDepartment of Otorhinolaryngology, University Hospital Essen, University Duisburg-Essen, 45147 Essen, Germany.
Jadwiga JablonskaDepartment of Otorhinolaryngology, University Hospital Essen, University Duisburg-Essen, 45147 Essen, Germany.ORCID 0000-0003-1490-2542
University of Duisburg-Essen · DEGerman Cancer Research Center · DE

Funding

DFG, Deutsche Krebshilfe DFG/ JA 2461/2-1, DFG/ JA 2461/5-1 and DFG/ JA 2461/7-1; (111647)
6 · The paper itself

Abstract

The role of neutrophils during cancer formation and elimination is diverse. Here, for the first time, we investigate neutrophil helper cells (N

Indexed as

B cellsB helper neutrophilshead-and-neck cancerhead-and-neck squamous cell carcinomalymph nodesNBHneutrophilsregional lymph nodes

Identifiers

PMID34205654
PMCPMC8234083
OpenAlexW3175327514

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.