Evidence map›Paper›PMID 34205581›Full record

ArticleLife (Basel, Switzerland)2021

Impact TMPRSS2-ERG Molecular Subtype on Prostate Cancer Recurrence.

Anastasiya A Kobelyatskaya, Elena A Pudova, Anastasiya V Snezhkina, Maria S Fedorova, Vladislav S Pavlov, Zulfiya G Guvatova, Maria V Savvateeva, Nataliya V Melnikova, Alexey A Dmitriev, Dmitry Y Trofimov and 6 more

Open access · goldAbstract read
In one paragraph

Article in Life (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.8field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Contemporary review of prognostic markers of prostate cancer from a pathologist perspective.Biomedical papers of the Medical Faculty of the University Palacky, Olomouc, Czechoslovakia · 2025
    Review
  3. Review
  4. Exploring therapeutic applications ofFrontiers in oncology · 2025
    Review
  5. Article
  6. Article
  7. Review
  8. Article
  9. International journal of molecular sciences · 2022
    Article
  10. Article
  11. The Expression of Proto-OncogeneInternational journal of molecular sciences · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 4 institutions in 1 country.

Anastasiya A KobelyatskayaEngelhardt Institute of Molecular Biology, Russian Academy of Sciences, 119991 Moscow, Russia.ORCID 0000-0002-7174-204X
Elena A PudovaEngelhardt Institute of Molecular Biology, Russian Academy of Sciences, 119991 Moscow, Russia.ORCID 0000-0002-5492-1361
Anastasiya V SnezhkinaEngelhardt Institute of Molecular Biology, Russian Academy of Sciences, 119991 Moscow, Russia.ORCID 0000-0002-4421-4364
Maria S FedorovaEngelhardt Institute of Molecular Biology, Russian Academy of Sciences, 119991 Moscow, Russia.ORCID 0000-0002-6893-4673
Vladislav S PavlovEngelhardt Institute of Molecular Biology, Russian Academy of Sciences, 119991 Moscow, Russia.ORCID 0000-0002-2942-6393
Zulfiya G GuvatovaEngelhardt Institute of Molecular Biology, Russian Academy of Sciences, 119991 Moscow, Russia.ORCID 0000-0003-3494-9807
Maria V SavvateevaEngelhardt Institute of Molecular Biology, Russian Academy of Sciences, 119991 Moscow, Russia.
Nataliya V MelnikovaEngelhardt Institute of Molecular Biology, Russian Academy of Sciences, 119991 Moscow, Russia.ORCID 0000-0001-8083-3018
Alexey A DmitrievEngelhardt Institute of Molecular Biology, Russian Academy of Sciences, 119991 Moscow, Russia.ORCID 0000-0002-6827-9584
Dmitry Y TrofimovGynecology and Perinatology named after Academician V.I. Kulakov, National Medical Research Center for Obstetrics, Ministry of Health of the Russian Federation, 117997 Moscow, Russia.
Gennady T SukhikhGynecology and Perinatology named after Academician V.I. Kulakov, National Medical Research Center for Obstetrics, Ministry of Health of the Russian Federation, 117997 Moscow, Russia.
Kirill M NyushkoNational Medical Research Radiological Center, Ministry of Health of the Russian Federation, 125284 Moscow, Russia.ORCID 0000-0002-4171-6211
Boris Y AlekseevNational Medical Research Radiological Center, Ministry of Health of the Russian Federation, 125284 Moscow, Russia.
Sergey V RazinInstitute of Gene Biology, Russian Academy of Sciences, 119334 Moscow, Russia.ORCID 0000-0003-1976-8661
George S KrasnovEngelhardt Institute of Molecular Biology, Russian Academy of Sciences, 119991 Moscow, Russia.ORCID 0000-0002-6493-8378
Anna V KudryavtsevaEngelhardt Institute of Molecular Biology, Russian Academy of Sciences, 119991 Moscow, Russia.ORCID 0000-0002-3722-8207
Engelhardt Institute of Molecular Biology · RUMinistry of Health of the Russian Federation · RUNational Medical Research Center for Obstetrics, Gynecology and Perinatology named after Academician V.I.Kulakov of the Ministry of Healthcare of the Russian Federation · RUInstitute of Gene Biology · RU

Funding

Russian Science Foundation 18-75-10127
6 · The paper itself

Abstract

Currently, seven molecular subtypes of prostate cancer (PCa) are known, the most common of which being the subtype characterized by the presence of the TMPRSS2-ERG fusion transcript. While there is a considerable amount of work devoted to the influence of this transcript on the prognosis of the disease, data on its role in the progression and prognosis of PCa remain controversial. The present study is devoted to the analysis of the association between the TMPRSS2-ERG transcript and the biochemical recurrence of PCa. The study included two cohorts: the RNA-Seq sample of Russian patients with PCa (

Indexed as

gene expressionprostate cancerRNA–SeqTMPRSS2–ERG molecular subtypetumor recurrence

Identifiers

PMID34205581
PMCPMC8234735
OpenAlexW3173664143

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.