Evidence map›Paper›PMID 34205572›Full record

ReviewCancers2021

Response Prediction and Evaluation Using PET in Patients with Solid Tumors Treated with Immunotherapy.

Frank J Borm, Jasper Smit, Daniela E Oprea-Lager, Maurits Wondergem, John B A G Haanen, Egbert F Smit, Adrianus J de Langen

Abstract readReview
In one paragraph

Review in Cancers, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Circulating Tumor DNA and [Diagnostics (Basel, Switzerland) · 2025
    Article
  3. Review
  4. Article
  5. Article
  6. Review
  7. Article
  8. Immuno-Imaging (PET/SPECT)-Quo Vadis?Molecules (Basel, Switzerland) · 2022
    Review
  9. Review
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Frank J BormDepartment of Pulmonary Diseases, Leiden University Medical Centre, 2333 ZA Leiden, The Netherlands.
Jasper SmitDepartment of Pulmonary Diseases, Leiden University Medical Centre, 2333 ZA Leiden, The Netherlands.
Daniela E Oprea-LagerDepartment of Radiology & Nuclear Medicine, Cancer Center Amsterdam, Amsterdam University Medical Centers (Location VU University Medical Center), 1081 HV Amsterdam, The Netherlands.
Maurits WondergemDepartment of Nuclear Medicine, NKI-AvL, 1066 CX Amsterdam, The Netherlands.
John B A G HaanenDepartment of Medical Oncology, NKI-AvL, 1066 CX Amsterdam, The Netherlands.
Egbert F SmitDepartment of Thoracic Oncology, NKI-AvL, 1066 CX Amsterdam, The Netherlands.
Adrianus J de LangenDepartment of Thoracic Oncology, NKI-AvL, 1066 CX Amsterdam, The Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In multiple malignancies, checkpoint inhibitor therapy has an established role in the first-line treatment setting. However, only a subset of patients benefit from checkpoint inhibition, and as a result, the field of biomarker research is active. Molecular imaging with the use of positron emission tomography (PET) is one of the biomarkers that is being studied. PET tracers such as conventional

Indexed as

biomarkerimmunotherapymelanomaNSCLCpositron emission tomography

Identifiers

PMID34205572
PMCPMC8234914

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.