Evidence map›Paper›PMID 34205541›Full record

ArticleBiosensors2021

Electrochemical Immunosensing of ST2: A Checkpoint Target in Cancer Diseases.

Rebeca M Torrente-Rodríguez, Cristina Muñoz-San Martín, Maria Gamella, María Pedrero, Neus Martínez-Bosch, Pilar Navarro, Pablo García de Frutos, José M Pingarrón, Susana Campuzano

Open access · goldAbstract read
In one paragraph

Article in Biosensors, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.9field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Rebeca M Torrente-RodríguezDepartamento de Química Analítica, Facultad de CC. Químicas, Universidad Complutense de Madrid, 28040 Madrid, Spain.
Cristina Muñoz-San MartínDepartamento de Química Analítica, Facultad de CC. Químicas, Universidad Complutense de Madrid, 28040 Madrid, Spain.ORCID 0000-0002-8324-0709
Maria GamellaDepartamento de Química Analítica, Facultad de CC. Químicas, Universidad Complutense de Madrid, 28040 Madrid, Spain.
María PedreroDepartamento de Química Analítica, Facultad de CC. Químicas, Universidad Complutense de Madrid, 28040 Madrid, Spain.ORCID 0000-0002-2047-396X
Neus Martínez-BoschCancer Research Program, Hospital del Mar Medical Research Institute (IMIM), Unidad Asociada IIBB-CSIC, 08003 Barcelona, Spain.
Pilar NavarroCancer Research Program, Hospital del Mar Medical Research Institute (IMIM), Unidad Asociada IIBB-CSIC, 08003 Barcelona, Spain.
Pablo García de FrutosDepartamento de Muerte y Proliferación Celular, Instituto de Investigaciones Biomédicas de Barcelona-Centro Superior de Investigaciones Científicas (IIBB-CSIC), 08036 Barcelona, Spain.ORCID 0000-0003-1547-1190
José M PingarrónDepartamento de Química Analítica, Facultad de CC. Químicas, Universidad Complutense de Madrid, 28040 Madrid, Spain.ORCID 0000-0003-2271-1383
Susana CampuzanoDepartamento de Química Analítica, Facultad de CC. Químicas, Universidad Complutense de Madrid, 28040 Madrid, Spain.ORCID 0000-0002-9928-6613
Universidad Complutense de Madrid · ESInstitut d'Investigacions Biomèdiques de Barcelona · ESHospital Del Mar · ES

Funding

AES-ISCIII/FEDER PI20/00625Comunidad de Madrid S2018/NMT-4349Ministerio de Ciencia e Innovación PID2019-103899RB-I00Ministerio de Ciencia, Innovación y Universidades RTI2018-095672-B-I00
6 · The paper itself

Abstract

A magnetic beads (MB)-involved amperometric immunosensor for the determination of ST2, a member of the IL1 receptor family, is reported in this work. The method utilizes a sandwich immunoassay and disposable screen-printed carbon electrodes (SPCEs). Magnetic immunoconjugates built on the surface of carboxylic acid-microsized magnetic particles (HOOC-MBs) were used to selectively capture ST2. A biotinylated secondary antibody further conjugated with a streptavidin peroxidase conjugate (Strep-HRP) was used to accomplish the sandwiching of the target protein. The immune platform exhibits great selectivity and a low limit of detection (39.6 pg mL

Indexed as

Biosensing TechniquesImmunoassayAntibodiesCarbonElectrochemical TechniquesElectrodesEnzyme-Linked Immunosorbent AssayHumansHydrogen PeroxideLimit of DetectionMagneticsNeoplasmsAntibodiesCarbonHydrogen Peroxideelectrochemical immune platformhuman ST2pancreatic cancerplasma

Identifiers

PMID34205541
PMCPMC8234531
OpenAlexW3174975724

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.