Evidence map›Paper›PMID 34205536›Full record

ArticleJournal of clinical medicine2021

B-Type Natriuretic Peptides and High-Sensitive Troponin I as COVID-19 Survival Factors: Which One Is the Best Performer?

Renato de Falco, Maria Vargas, Daniela Palma, Marcella Savoia, Anna Miscioscia, Biagio Pinchera, Martina Vano, Giuseppe Servillo, Ivan Gentile, Giuliana Fortunato

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.7field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 11 citations in OpenAlex.

  1. COVID-19, Myocarditis and Pericarditis.Circulation research · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Renato de FalcoDepartment of Biochemistry and Medical Biotechnology, University of Naples "Federico II", Via Sergio Pansini 5, 80131 Naples, Italy.
Maria VargasDepartment of Neuroscience, Reproductive and Odontostomatological Sciences, University of Naples "Federico II", Via Sergio Pansini 5, 80131 Naples, Italy.
Daniela PalmaDepartment of Biochemistry and Medical Biotechnology, University of Naples "Federico II", Via Sergio Pansini 5, 80131 Naples, Italy.
Marcella SavoiaDepartment of Biochemistry and Medical Biotechnology, University of Naples "Federico II", Via Sergio Pansini 5, 80131 Naples, Italy.
Anna MisciosciaDepartment of Biochemistry and Medical Biotechnology, University of Naples "Federico II", Via Sergio Pansini 5, 80131 Naples, Italy.
Biagio PincheraDepartment of Clinical Medicine and Surgery, Section of Infectious Diseases, University of Naples "Federico II", Via Sergio Pansini 5, 80131 Naples, Italy.ORCID 0000-0002-8685-5434
Martina VanoDepartment of Biochemistry and Medical Biotechnology, University of Naples "Federico II", Via Sergio Pansini 5, 80131 Naples, Italy.
Giuseppe ServilloDepartment of Neuroscience, Reproductive and Odontostomatological Sciences, University of Naples "Federico II", Via Sergio Pansini 5, 80131 Naples, Italy.
Ivan GentileDepartment of Clinical Medicine and Surgery, Section of Infectious Diseases, University of Naples "Federico II", Via Sergio Pansini 5, 80131 Naples, Italy.ORCID 0000-0002-5199-8451
Giuliana FortunatoDepartment of Biochemistry and Medical Biotechnology, University of Naples "Federico II", Via Sergio Pansini 5, 80131 Naples, Italy.
Federico II University Hospital · ITUniversity of Naples Federico II · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Increased concentrations of B-type natriuretic peptide (BNP), N-terminal pro-B-type natriuretic peptide (NT-proBNP) and high-sensitivity troponin I (HsTnI) in COVID-19 patients have already been reported. The aim of this study is to evaluate which of these common markers of cardiac disease is the most useful predictor of fatal outcome in COVID-19 patients. One hundred and seventy-four patients affected with COVID-19 were recruited, and markers of cardiac disease and the clinical history of the patients were collected at admission in the infectious disease unit or intensive care unit. NT-proBNP, BNP and HsTnI values were higher in in-hospital non-surviving patients. Receiver operating characteristic (ROC) curve analysis of NT-proBNP, BNP and HsTnI was performed, with NT-proBNP (AUC = 0.951) and HsTnI (AUC = 0.947) being better performers (

Indexed as

BNPCOVID-19fatal outcomeNT-proBNPprognostic markerstroponin

Identifiers

PMID34205536
PMCPMC8235158
OpenAlexW3177486256

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.