Evidence map›Paper›PMID 34205473›Full record

ArticleMicromachines2021

Implantable Optrode Array for Optogenetic Modulation and Electrical Neural Recording.

Saeyeong Jeon, Youjin Lee, Daeho Ryu, Yoon Kyung Cho, Yena Lee, Sang Beom Jun, Chang-Hyeon Ji

Open access · goldAbstract read
In one paragraph

Article in Micromachines, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Saeyeong JeonDepartment of Electrical and Computer Engineering, Seoul National University, Seoul 08826, Korea.
Youjin LeeDepartment of Electronic and Electrical Engineering, Ewha Womans University, Seoul 03760, Korea.ORCID 0000-0002-7631-2057
Daeho RyuDepartment of Electrical and Computer Engineering, Seoul National University, Seoul 08826, Korea.
Yoon Kyung ChoDepartment of Electronic and Electrical Engineering, Ewha Womans University, Seoul 03760, Korea.
Yena LeeDepartment of Electronic and Electrical Engineering, Ewha Womans University, Seoul 03760, Korea.
Sang Beom JunDepartment of Electronic and Electrical Engineering, Ewha Womans University, Seoul 03760, Korea.ORCID 0000-0003-3912-250X
Chang-Hyeon JiDepartment of Electronic and Electrical Engineering, Ewha Womans University, Seoul 03760, Korea.ORCID 0000-0002-9299-8079
Ewha Womans University · KRSeoul National University · KR

Funding

National Research Foundation of Korea (NRF) funded by the Ministry of Science and ICT NRF-2019M3C1B8090805National Research Foundation of Korea (NRF) grant funded by the Korea government No. 2019R1A2C1088909
6 · The paper itself

Abstract

During the last decade, optogenetics has become an essential tool for neuroscience research due to its unrivaled feature of cell-type-specific neuromodulation. There have been several technological advances in light delivery devices. Among them, the combination of optogenetics and electrophysiology provides an opportunity for facilitating optogenetic approaches. In this study, a novel design of an optrode array was proposed for realizing optical modulation and electrophysiological recording. A 4 × 4 optrode array and five-channel recording electrodes were assembled as a disposable part, while a reusable part comprised an LED (light-emitting diode) source and a power line. After the characterization of the intensity of the light delivered at the fiber tips, in vivo animal experiment was performed with transgenic mice expressing channelrhodopsin, showing the effectiveness of optical activation and neural recording.

Indexed as

channelrhodopsinelectrodeelectrophysiologyoptogeneticsoptrode

Identifiers

PMID34205473
PMCPMC8234104
OpenAlexW3174112474

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.