Evidence map›Paper›PMID 34205428›Full record

ArticleDiagnostics (Basel, Switzerland)2021

Atypical Ductal Hyperplasia after Vacuum-Assisted Breast Biopsy: Can We Reduce the Upgrade to Breast Cancer to an Acceptable Rate?

Luca Nicosia, Antuono Latronico, Francesca Addante, Rossella De Santis, Anna Carla Bozzini, Marta Montesano, Samuele Frassoni, Vincenzo Bagnardi, Giovanni Mazzarol, Oriana Pala and 4 more

Open access · goldAbstract read
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
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  3. Article
  4. Review
  5. Article
  6. Article
  7. Review
  8. Should low-risk DCIS lose the cancer label? An evidence review.Breast cancer research and treatment · 2023
    Review
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  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 5 institutions in 1 country.

Luca NicosiaDepartment of Breast Radiology, IEO European Institute of Oncology, IRCCS, 20141 Milan, Italy.
Antuono LatronicoDepartment of Breast Radiology, IEO European Institute of Oncology, IRCCS, 20141 Milan, Italy.
Francesca AddanteDepartment of Emergency and Organ Transplantation, Section of Anatomic Pathology, School of Medicine, University "Aldo Moro", 70124 Bari, Italy.
Rossella De SantisPostgraduate School in Radiology, University of Milan, 20122 Milan, Italy.
Anna Carla BozziniDepartment of Breast Radiology, IEO European Institute of Oncology, IRCCS, 20141 Milan, Italy.
Marta MontesanoDepartment of Breast Radiology, IEO European Institute of Oncology, IRCCS, 20141 Milan, Italy.
Samuele FrassoniDepartment of Statistics and Quantitative Methods, University of Milan-Bicocca, 20126 Milan, Italy.
Vincenzo BagnardiDepartment of Statistics and Quantitative Methods, University of Milan-Bicocca, 20126 Milan, Italy.
Giovanni MazzarolDivision of Pathology and Laboratory Medicine, IEO European Institute of Oncology, IRCCS, 20141 Milan, Italy.
Oriana PalaDivision of Pathology and Laboratory Medicine, IEO European Institute of Oncology, IRCCS, 20141 Milan, Italy.
Matteo LazzeroniDivision of Cancer Prevention and Genetics, IEO European Institute of Oncology IRCCS, 20141 Milan, Italy.ORCID 0000-0002-2162-4002
Germana LissidiniDivision of Breast Surgery, IEO European Institute of Oncology, IRCCS, 20141 Milan, Italy.
Mauro Giuseppe MastropasquaDepartment of Emergency and Organ Transplantation, Section of Anatomic Pathology, School of Medicine, University "Aldo Moro", 70124 Bari, Italy.ORCID 0000-0002-8306-0839
Enrico CassanoDepartment of Breast Radiology, IEO European Institute of Oncology, IRCCS, 20141 Milan, Italy.
Istituti di Ricovero e Cura a Carattere Scientifico · ITEuropean Institute of Oncology · ITUniversity of Bari Aldo Moro · ITUniversity of Milano-Bicocca · ITUniversity of Milan · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

(1) Background: to evaluate which factors can reduce the upgrade rate of atypical ductal hyperplasia (ADH) to in situ or invasive carcinoma in patients who underwent vacuum-assisted breast biopsy (VABB) and subsequent surgical excision. (2) Methods: 2955 VABBs were reviewed; 141 patients with a diagnosis of ADH were selected for subsequent surgical excision. The association between patients' characteristics and the upgrade rate to breast cancer was evaluated in both univariate and multivariate analyses. (3) Results: the upgrade rates to ductal carcinoma in situ (DCIS) and invasive carcinoma (IC) were, respectively, 29.1% and 7.8%. The pooled upgrade rate to DCIS or IC was statistically lower at univariate analysis, considering the following parameters: complete removal of the lesion (

Indexed as

atypical duct hyperplasiaBIRADSbreast biopsybreast cancerbreast surgeryovertreatmentupgrade to cancer

Identifiers

PMID34205428
PMCPMC8259513
OpenAlexW3175098076

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.