ArticleCancers2021
Diagnostic Yield of Endoscopic Ultrasound-Guided Liver Biopsy in Comparison to Percutaneous Liver Biopsy: A Two-Center Experience.
Article in Cancers, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
28 citing papers in PubMed, 1 synthesis or guideline pooled it, 36 citations in OpenAlex.
- Diagnostic and therapeutic role of endoscopic ultrasound in liver diseases: A systematic review and meta-analysis.World journal of gastroenterology · 2024Pooled it
- A cost-effective measure to prevent hemorrhage in ultrasound-guided percutaneous liver biopsy.BMC gastroenterology · 2025Trial
- Endo-Hepatology: Paradigm Shift in Endosonographic Diagnosis for Liver Disease to Digestive Endoscopy.Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society · 2026Review
- Article
- The role of EUS in liver transplantation.Hepatology forum · 2026Review
- Endoscopic ultrasound-guided liver biopsy using a 22G fine-needle biopsy needle and slow pull technique: A tertiary center experience.PloS one · 2026Observational
- Computed tomography-guided percutaneous biopsy for assessing tumor heterogeneity in neuroendocrine tumor metastases to the liver.World journal of radiology · 2025Article
- Surface area outcomes in EUS-guided liver biopsy: a comparative study of Franseen and Fork-tip needles.BMC gastroenterology · 2025Article
- Advances in Endo-Hepatology: The Role of Endoscopic Ultrasound in the Management of Portal Hypertension.Diagnostics (Basel, Switzerland) · 2025Review
- Getting the optimal technique for EUS-guided liver biopsy: are we there?Gastroenterology report · 2025Article
- Optimal techniques for obtaining superior liver specimens at endoscopic ultrasound-guided biopsy: a pilot study on pigs.Gastroenterology report · 2025Article
- Is endoscopic ultrasound a promising technique in the diagnosis and treatment of liver diseases?World journal of gastroenterology · 2024Article
- Review
- Alpha-fetoprotein, glypican-3, and kininogen-1 as biomarkers for the diagnosis of hepatocellular carcinoma.International journal of clinical and experimental pathology · 2024Review
- Role of endoscopic ultrasound and endoscopic ultrasound-guided tissue acquisition in diagnosing hepatic focal lesions.World journal of methodology · 2023Article
- Diagnostic efficacy of endoscopic ultrasound-guided liver biopsy for diffuse liver diseases and its predictors - a multicentric retrospective analysis.Clinical and experimental hepatology · 2023Article
- Article
- Advances in Endoscopic Ultrasound (EUS)-Guided Liver Biopsy.Diagnostics (Basel, Switzerland) · 2023Review
- EUS-guided left lobe liver biopsy: Safer modality with similar diagnostic yield as right lobe: a pilot study.Endoscopy international open · 2023Article
- Endoscopic Ultrasound-Guided Fine-Needle Biopsy versus Fine-Needle Aspiration in the Diagnosis of Focal Liver Lesions: Prospective Head-to-Head Comparison.Diagnostics (Basel, Switzerland) · 2022Article
Corrections and comments
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Authors and funding
7 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
There is scarce and conflicting evidence on the comparison between endoscopic ultrasound (EUS) and percutaneous (PC)-guided liver biopsy (LB). The aim of this study was to compare the two approaches in a series of patients with parenchymal and focal liver lesions. Fifty-four patients undergoing EUS-LB in two high-volume centers between 2017 and 2021 were compared to 62 patients who underwent PC-LB. The primary outcome was diagnostic adequacy rate. The secondary outcomes were diagnostic accuracy, total sample length (TSL), number of complete portal tracts (CPTs), procedural duration, and adverse events. Variables were compared using the Chi-square and Mann-Whitney test. Median age was 56 years (interquartile range 48-69) in the EUS-LB group and 54 years (45-67) in the PC-LB group with most patients being male. Indication for LB was due to parenchymal disease in 50% of patients, whereas the other patients underwent LB due to focal liver lesions. Diagnostic adequacy was 100% in PC-LB and 94.4% in the EUS-LB group (
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.