Evidence map›Paper›PMID 34205376›Full record

ArticleGenes2021

Two

Chiara Vancheri, Elena Morini, Francesca Romana Prandi, Elie Alkhoury, Roberto Celotto, Francesco Romeo, Giuseppe Novelli, Francesca Amati

Open access · goldAbstract read
In one paragraph

Article in Genes, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.3field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Chiara VancheriGenetics Unit, Department of Biomedicine and Prevention, University of Rome "Tor Vergata", 00133 Rome, Italy.
Elena MoriniGenetics Unit, Department of Biomedicine and Prevention, University of Rome "Tor Vergata", 00133 Rome, Italy.
Francesca Romana PrandiUnit of Cardiology, University Hospital "Tor Vergata", 00133 Rome, Italy.ORCID 0000-0003-1878-8871
Elie AlkhouryUnit of Cardiology, University Hospital "Tor Vergata", 00133 Rome, Italy.
Roberto CelottoUnit of Cardiology, University Hospital "Tor Vergata", 00133 Rome, Italy.ORCID 0000-0003-1837-5997
Francesco RomeoUnit of Cardiology, University Hospital "Tor Vergata", 00133 Rome, Italy.
Giuseppe NovelliGenetics Unit, Department of Biomedicine and Prevention, University of Rome "Tor Vergata", 00133 Rome, Italy.ORCID 0000-0002-7781-602X
Francesca AmatiGenetics Unit, Department of Biomedicine and Prevention, University of Rome "Tor Vergata", 00133 Rome, Italy.ORCID 0000-0003-2209-2156
University of Rome Tor Vergata · ITSaint Camillus International University of Health and Medical Sciences · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Primary prevention is crucial for coronary heart disease (CAD) and the identification of new reliable biomarkers might help risk stratification or predict adverse coronary events. Alternative splicing (AS) is a less investigated genetic factors implicated in CAD etiology. We performed an RNA-seq study on PBMCs from CAD patients and control subjects (CTR) and observed 113 differentially regulated AS events (24 up and 89 downregulated) in 86 genes. The

Indexed as

Alternative SplicingAgedBiomarkersCells, CulturedCoronary Artery DiseaseFemaleGPI-Linked ProteinsHumansMaleMiddle AgedMyocardial InfarctionPilot ProjectsBiomarkersGPI-Linked ProteinsRECK protein, humanalternative splicing eventbiomarkerscoronary artery diseaseRECKsplicing variants

Identifiers

PMID34205376
PMCPMC8234100
OpenAlexW3175173658

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.