Evidence map›Paper›PMID 34205355›Full record

ArticleMolecules (Basel, Switzerland)2021

Natural Product Rottlerin Derivatives Targeting Quorum Sensing.

Dittu Suresh, Shekh Sabir, Tsz Tin Yu, Daniel Wenholz, Theerthankar Das, David StC Black, Naresh Kumar

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.4field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. UsingFrontiers in pharmacology · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Dittu SureshSchool of Chemistry, The University of New South Wales, Sydney, NSW 2052, Australia.
Shekh SabirSchool of Chemistry, The University of New South Wales, Sydney, NSW 2052, Australia.ORCID 0000-0002-3962-3040
Tsz Tin YuSchool of Chemistry, The University of New South Wales, Sydney, NSW 2052, Australia.ORCID 0000-0002-8484-7342
Daniel WenholzSchool of Chemistry, The University of New South Wales, Sydney, NSW 2052, Australia.
Theerthankar DasDepartment of Infectious Diseases and Immunology, School of Medical Sciences, The University of Sydney, Sydney, NSW 2006, Australia.
David StC BlackSchool of Chemistry, The University of New South Wales, Sydney, NSW 2052, Australia.ORCID 0000-0001-9300-4737
Naresh KumarSchool of Chemistry, The University of New South Wales, Sydney, NSW 2052, Australia.
UNSW Sydney · AUThe University of Sydney · AU

Funding

Australian Research Council DP180100845
6 · The paper itself

Abstract

Rottlerin is a natural product consisting of chalcone and flavonoid scaffolds, both of which have previously shown quorum sensing (QS) inhibition in various bacteria. Therefore, the unique rottlerin scaffold highlights great potential in inhibiting the QS system of

Indexed as

AcetophenonesAnti-Bacterial AgentsBenzopyransBiofilmsBiological ProductsFlavonoidsMicrobial Sensitivity TestsPseudomonas aeruginosaPyocyanineQuorum SensingAcetophenonesAnti-Bacterial AgentsBenzopyransBiological ProductsFlavonoidsPyocyaninerottlerinnatural productsPseudomonas aeruginosapyranochromene chalconequorum sensing inhibitorsrottlerin

Identifiers

PMID34205355
PMCPMC8235494
OpenAlexW3175934287

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.