Evidence map›Paper›PMID 34205274›Full record

ArticleInternational journal of molecular sciences2021

FMRP Interacts with RARα in Synaptic Retinoic Acid Signaling and Homeostatic Synaptic Plasticity.

Esther Park, Anthony G Lau, Kristin L Arendt, Lu Chen

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Article
  6. Hyperexcitability and Homeostasis in Fragile X Syndrome.Frontiers in molecular neuroscience · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Esther ParkDepartments of Neurosurgery, Neuropsychiatry and Behavioral Sciences, Stanford University School of Medicine, 265 Campus Drive, Stanford, CA 94305-5453, USA.
Anthony G LauDepartments of Neurosurgery, Neuropsychiatry and Behavioral Sciences, Stanford University School of Medicine, 265 Campus Drive, Stanford, CA 94305-5453, USA.
Kristin L ArendtDepartments of Neurosurgery, Neuropsychiatry and Behavioral Sciences, Stanford University School of Medicine, 265 Campus Drive, Stanford, CA 94305-5453, USA.
Lu ChenDepartments of Neurosurgery, Neuropsychiatry and Behavioral Sciences, Stanford University School of Medicine, 265 Campus Drive, Stanford, CA 94305-5453, USA.
Stanford University · US

Funding

Role of synaptotagmins and neurexin ligands in homeostatic synaptic plasticityP50MH086403 · NIMH · STANFORD UNIVERSITY · PI MALENKA, ROBERT C · 2009 to 2019
$18.4M
Project 3P50HD104458 · NICHD · EMORY UNIVERSITY · PI JIN, PENG · 2020 to 2024
$8.1M
Developmental Pathophysiology of Synapses in a Mouse Model of Fragile X SyndromeR01HD084215 · NICHD · STANFORD UNIVERSITY · PI CHEN, LU · 2014 to 2018
$3.3M
A molecular investigation of retinoic acid-dependent homeostatic synaptic plasticityR01NS115660 · NINDS · STANFORD UNIVERSITY · PI CHEN, LU · 2020 to 2024
$2.9M
Regulation of synaptic transmission by retinoic acid signalingR01MH091193 · NIMH · STANFORD UNIVERSITY · PI CHEN, LU · 2011 to 2015
$2.3M
Eunice Kennedy Shriver National Institute of Child Health and Human Development HD084215Eunice Kennedy Shriver National Institute of Child Health and Human Development HD104458NICHD NIH HHS P50 HD104458NICHD NIH HHS R01 HD084215NIMH NIH HHS MH086403NIMH NIH HHS R01 MH091193NINDS NIH HHS NS11566001NINDS NIH HHS R01 NS115660
6 · The paper itself

Abstract

The fragile X syndrome (FXS) is an X-chromosome-linked neurodevelopmental disorder with severe intellectual disability caused by inactivation of the fragile X mental retardation 1 (

Indexed as

Neuronal PlasticityAnimalsFemaleFragile X Messenger Ribonucleoprotein 1HomeostasisMaleMiceMice, KnockoutRetinoic Acid Receptor alphaTretinoinFmr1 protein, mouseFragile X Messenger Ribonucleoprotein 1Retinoic Acid Receptor alphaTretinoinFMRPfragile X syndromehomeostatic synaptic plasticityretinoic acid signaling

Identifiers

PMID34205274
PMCPMC8235556
OpenAlexW3177149341

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.