Evidence map›Paper›PMID 34205064›Full record

ArticleInternational journal of molecular sciences2021

Cortactin Is Required for Efficient FAK, Src and Abl Tyrosine Kinase Activation and Phosphorylation of

Jakob Knorr, Irshad Sharafutdinov, Florian Fiedler, Delara Soltan Esmaeili, Manfred Rohde, Klemens Rottner, Steffen Backert, Nicole Tegtmeyer

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 12 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Frontiers in cell and developmental biology · 2025
    Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Cortactin Promotes Effective AGS Cell Scattering byPathogens (Basel, Switzerland) · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Jakob KnorrDepartment of Biology, Division of Microbiology, Friedrich-Alexander University of Erlangen-Nuremberg, 91058 Erlangen, Germany.
Irshad SharafutdinovDepartment of Biology, Division of Microbiology, Friedrich-Alexander University of Erlangen-Nuremberg, 91058 Erlangen, Germany.ORCID 0000-0002-9873-9676
Florian FiedlerDepartment of Biology, Division of Microbiology, Friedrich-Alexander University of Erlangen-Nuremberg, 91058 Erlangen, Germany.
Delara Soltan EsmaeiliDepartment of Biology, Division of Microbiology, Friedrich-Alexander University of Erlangen-Nuremberg, 91058 Erlangen, Germany.
Manfred RohdeCentral Facility for Microscopy, Helmholtz Centre for Infection Research, 38124 Braunschweig, Germany.
Klemens RottnerDepartment of Cell Biology, Helmholtz Centre for Infection Research, 38124 Braunschweig, Germany.ORCID 0000-0003-4244-4198
Steffen BackertDepartment of Biology, Division of Microbiology, Friedrich-Alexander University of Erlangen-Nuremberg, 91058 Erlangen, Germany.ORCID 0000-0002-8948-8254
Nicole TegtmeyerDepartment of Biology, Division of Microbiology, Friedrich-Alexander University of Erlangen-Nuremberg, 91058 Erlangen, Germany.
Friedrich-Alexander-Universität Erlangen-Nürnberg · DEHelmholtz Centre for Infection Research · DE

Funding

Deutsche Forschungsgemeinschaft TE776/3 1
6 · The paper itself

Abstract

Cortactin is a well-known regulatory protein of the host actin cytoskeleton and represents an attractive target of microbial pathogens like

Indexed as

Antigens, BacterialBacterial ProteinsFocal Adhesion Kinase 1Gene Expression Regulation, BacterialHelicobacter InfectionsHelicobacter pyloriHost-Pathogen InteractionsHumansOncogene Proteins v-ablPhosphorylationsrc-Family KinasesAntigens, BacterialBacterial ProteinscagA protein, Helicobacter pyloriFocal Adhesion Kinase 1Oncogene Proteins v-ablPTK2 protein, humansrc-Family KinasesAblcancercortactinFAKHelicobacterpathogenesispathogenicity islandsignalingSrcvirulence

Identifiers

PMID34205064
PMCPMC8199859
OpenAlexW3170259687

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.