Evidence map›Paper›PMID 34204991›Full record

ReviewJournal of clinical medicine2021

A Comprehensive Review of Tic Disorders in Children.

Keisuke Ueda, Kevin J Black

Open access · goldAbstract readReview
In one paragraph

Review in Journal of clinical medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 74 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
74citing papers in PubMed, 1 pooled it
13.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

74 citing papers in PubMed, 1 synthesis or guideline pooled it, 140 citations in OpenAlex.

  1. Pooled it
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  17. The Prevalence of Tic Disorders in Poland: Regional and Sex Differences.Tremor and other hyperkinetic movements (New York, N.Y.) · 2026
    Article
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  19. Article
  20. Article

14 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Keisuke UedaDepartment of Neurology, Washington University School of Medicine, St. Louis, MO 63110, USA.ORCID 0000-0003-4087-6018
Kevin J BlackDepartment of Neurology, Washington University School of Medicine, St. Louis, MO 63110, USA.ORCID 0000-0002-6921-9567
Washington University in St. Louis · US

Funding

The New Tics Study: A Novel Approach to Pathophysiology and Cause of Tic DisordersR01MH104030 · NIMH · WASHINGTON UNIVERSITY · PI BLACK, KEVIN J · 2017 to 2021
$3.3M
NIMH NIH HHS R01 MH104030NIMH NIH HHS R01MH104030
6 · The paper itself

Abstract

Tics are characterized by sudden, rapid, recurrent, nonrhythmic movement or vocalization, and are the most common movement disorders in children. Their onset is usually in childhood and tics often will diminish within one year. However, some of the tics can persist and cause various problems such as social embarrassment, physical discomfort, or emotional impairments, which could interfere with daily activities and school performance. Furthermore, tic disorders are frequently associated with comorbid neuropsychiatric symptoms, which can become more problematic than tic symptoms. Unfortunately, misunderstanding and misconceptions of tic disorders still exist among the general population. Understanding tic disorders and their comorbidities is important to deliver appropriate care to patients with tics. Several studies have been conducted to elucidate the clinical course, epidemiology, and pathophysiology of tics, but they are still not well understood. This article aims to provide an overview about tics and tic disorders, and recent findings on tic disorders including history, definition, diagnosis, epidemiology, etiology, diagnostic approach, comorbidities, treatment and management, and differential diagnosis.

Indexed as

comorbid symptomsdifferential diagnosisnatural coursepediatric movement disorderpremonitory urgeticsTourette syndrome

Identifiers

PMID34204991
PMCPMC8199885
OpenAlexW3168976557

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.