Evidence map›Paper›PMID 34204966›Full record

ArticleAntioxidants (Basel, Switzerland)2021

Protective Effects of Oroxylin A on Retinal Ganglion Cells in Experimental Model of Anterior Ischemic Optic Neuropathy.

Jia-Ying Chien, Shu-Fang Lin, Yu-Yau Chou, Chi-Ying F Huang, Shun-Ping Huang

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Antioxidants (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Jia-Ying ChienInstitute of Medical Sciences, Tzu Chi University, Hualien 970, Taiwan.ORCID 0000-0002-3438-9435
Shu-Fang LinInstitute of Clinical Medicine, National Yang Ming Chiao Tung University, Taipei 112, Taiwan.
Yu-Yau ChouDepartment of Molecular Biology and Human Genetics, Tzu Chi University, Hualien 970, Taiwan.ORCID 0000-0001-9030-2173
Chi-Ying F HuangInstitute of Clinical Medicine, National Yang Ming Chiao Tung University, Taipei 112, Taiwan.ORCID 0000-0003-4898-4937
Shun-Ping HuangInstitute of Medical Sciences, Tzu Chi University, Hualien 970, Taiwan.
Tzu Chi University · TWNational Yang Ming Chiao Tung University · TW

Funding

Ministry of Science and Technology of TAIWAN 105-2628-B-320-002-MY3
6 · The paper itself

Abstract

Nonarteritic anterior ischemic optic neuropathy (NAION) is the most common cause of acute vision loss in older people, and there is no effective therapy. The effect of the systemic or local application of steroids for NAION patients remains controversial. Oroxylin A (OA) (5,7-dihydroxy-6-methoxyflavone) is a bioactive flavonoid extracted from

Indexed as

ischemic optic neuropathymicrogliaNrf2optical coherence tomography (OCT)Oroxylin Aoxidative stressretinal ganglion cellvisual evoked potential (VEP)

Identifiers

PMID34204966
PMCPMC8226497
OpenAlexW3168018834

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.