Evidence map›Paper›PMID 34204828›Full record

ArticleInternational journal of environmental research and public health2021

The Acute Effects of Exercise and Temperature on Regional mtDNA.

Mark L McGlynn, Halee Schnitzler, Robert Shute, Brent Ruby, Dustin Slivka

Open access · goldAbstract read
In one paragraph

Article in International journal of environmental research and public health, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. No Mitochondrial Related Transcriptional Changes in Human Skeletal Muscle after Local Heat Application.International journal of environmental research and public health · 2022
    Article
  3. Effect of local heat application during exercise on gene expression related to mitochondrial homeostasis.Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Mark L McGlynnSchool of Health and Kinesiology, University of Nebraska at Omaha, Omaha, NE 68182, USA.
Halee SchnitzlerSchool of Health and Kinesiology, University of Nebraska at Omaha, Omaha, NE 68182, USA.
Robert ShuteSchool of Health and Kinesiology, University of Nebraska at Omaha, Omaha, NE 68182, USA.
Brent RubySchool of Integrative Physiology and Athletic Training, University of Montana, Missoula, MT 59812, USA.
Dustin SlivkaSchool of Health and Kinesiology, University of Nebraska at Omaha, Omaha, NE 68182, USA.ORCID 0000-0001-7337-3770
University of Nebraska at Omaha · USUniversity of Montana · US

Funding

UNMC Structural Biology CoreP20GM103427 · NIGMS · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI Heather Colleen Jensen-Smith · 2012 to 2026
$59.2M
NIGMS NIH HHS P20GM103427
6 · The paper itself

Abstract

A reduced mitochondrial DNA (mtDNA) copy number, the ratio of mitochondrial DNA to genomic DNA (mtDNA:gDNA), has been linked with dysfunctional mitochondria. Exercise can acutely induce mtDNA damage manifested as a reduced copy number. However, the influence of a paired (exercise and temperature) intervention on regional mtDNA (MINor Arc and MAJor Arc) are unknown. Thus, the purpose of this study was to determine the acute effects of exercise in cold (7 °C), room temperature (20 °C), and hot (33 °C) ambient temperatures, on regional mitochondrial copy number (MINcn and MAJcn). Thirty-four participants (24.4 ± 5.1 yrs, 87.1 ± 22.1 kg, 22.3 ± 8.5 %BF, and 3.20 ± 0.59 L·min

Indexed as

DNA, MitochondrialExerciseCold TemperatureHot TemperatureHumansMitochondriaTemperatureDNA, Mitochondrialambient temperaturecopy numberexercisemitochondriamtDNAthermoregulation

Identifiers

PMID34204828
PMCPMC8296217
OpenAlexW3173014198

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.