Evidence map›Paper›PMID 34204738›Full record

ArticlePharmaceuticals (Basel, Switzerland)2021

Anti-Tumoral Effects of a (1

Alice Nicolai, Valentina Noemi Madia, Antonella Messore, Daniela De Vita, Alessandro De Leo, Davide Ialongo, Valeria Tudino, Elisabetta Tortorella, Luigi Scipione, Samanta Taurone and 5 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Pharmaceuticals (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.8field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 3 institutions in 1 country.

Alice NicolaiDepartment of Experimental Medicine, "Sapienza" University of Rome, Viale Regina Elena 324, 00161 Rome, Italy.
Valentina Noemi MadiaDipartimento di Chimica e Tecnologie del Farmaco, Istituto Pasteur-Fondazione Cenci Bolognetti, "Sapienza" Università di Roma, P.le Aldo Moro 5, 00185 Rome, Italy.ORCID 0000-0002-5724-612X
Antonella MessoreDipartimento di Chimica e Tecnologie del Farmaco, Istituto Pasteur-Fondazione Cenci Bolognetti, "Sapienza" Università di Roma, P.le Aldo Moro 5, 00185 Rome, Italy.
Daniela De VitaDepartment of Environmental Biology, "Sapienza" University of Rome, p.le Aldo Moro 5, 00185 Rome, Italy.
Alessandro De LeoDipartimento di Chimica e Tecnologie del Farmaco, Istituto Pasteur-Fondazione Cenci Bolognetti, "Sapienza" Università di Roma, P.le Aldo Moro 5, 00185 Rome, Italy.ORCID 0000-0001-5596-7217
Davide IalongoDipartimento di Chimica e Tecnologie del Farmaco, Istituto Pasteur-Fondazione Cenci Bolognetti, "Sapienza" Università di Roma, P.le Aldo Moro 5, 00185 Rome, Italy.ORCID 0000-0002-4672-2936
Valeria TudinoDipartimento di Chimica e Tecnologie del Farmaco, Istituto Pasteur-Fondazione Cenci Bolognetti, "Sapienza" Università di Roma, P.le Aldo Moro 5, 00185 Rome, Italy.
Elisabetta TortorellaDepartment of Experimental Medicine, "Sapienza" University of Rome, Viale Regina Elena 324, 00161 Rome, Italy.ORCID 0000-0003-4706-854X
Luigi ScipioneDipartimento di Chimica e Tecnologie del Farmaco, Istituto Pasteur-Fondazione Cenci Bolognetti, "Sapienza" Università di Roma, P.le Aldo Moro 5, 00185 Rome, Italy.ORCID 0000-0002-2006-7005
Samanta TauroneDepartment of Sensory Organs, "Sapienza" University of Rome, Viale del Policlinico 155, 00161 Rome, Italy.
Tiziano PergolizziDepartment of Sensory Organs, "Sapienza" University of Rome, Viale del Policlinico 155, 00161 Rome, Italy.
Marco ArticoDepartment of Sensory Organs, "Sapienza" University of Rome, Viale del Policlinico 155, 00161 Rome, Italy.ORCID 0000-0002-8786-7007
Roberto Di SantoDipartimento di Chimica e Tecnologie del Farmaco, Istituto Pasteur-Fondazione Cenci Bolognetti, "Sapienza" Università di Roma, P.le Aldo Moro 5, 00185 Rome, Italy.ORCID 0000-0002-4279-7666
Roberta CostiDipartimento di Chimica e Tecnologie del Farmaco, Istituto Pasteur-Fondazione Cenci Bolognetti, "Sapienza" Università di Roma, P.le Aldo Moro 5, 00185 Rome, Italy.
Susanna ScarpaDepartment of Experimental Medicine, "Sapienza" University of Rome, Viale Regina Elena 324, 00161 Rome, Italy.
Istituto Pasteur · ITPoliclinico Umberto I · ITSapienza University of Rome · IT

Funding

Sapienza Università di Roma Ateneo
6 · The paper itself

Abstract

Nocodazole is an antineoplastic agent that exerts its effects by depolymerizing microtubules. Herein we report a structural analog of nocodazole, a (1

Indexed as

apoptosisbenzimidazolesepithelial-mesenchymal transitionhead and neck squamous cell carcinomanocodazolepyrrolestubulin

Identifiers

PMID34204738
PMCPMC8231569
OpenAlexW3168872375

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.