ArticleMaterials (Basel, Switzerland)2021
Effects of Fatigue Damage on the Microscopic Modulus of Cortical Bone Using Nanoindentation.
Article in Materials (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
3 citing papers in PubMed.
- Integration of Bone Remodeling and Damage Accumulation: A Preliminary Computational Framework for Physiological and Pathological Responses.Acta biotheoretica · 2026Article
- A Modified Fatigue Life Prediction Model for Cyclic Hardening/Softening Steel.Materials (Basel, Switzerland) · 2025Article
- Spatiotemporal Characterization of Microstructure Morphology, Mechanical Properties and Bone Remodeling of Rat Tibia Under Uniaxial Compressive Overload Loading.Annals of biomedical engineering · 2024Article
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Authors and funding
4 authors.
Funding
Abstract
Alterations to the bone structure from cycle loadings can undermine its damage resistance at multiple scales. The accumulation of fatigue damage in a bone is commonly characterized by the reduction in the elastic modulus. In this study, nano-indentation was used for investigating microscopic damage evolution of bovine tibia samples subjected to fatigue loading. Indentation tests were conducted in the same 60 μm × 120 μm area with different degrees of damage, including fracture, and the evolution of reduced modulus was observed. The results showed that bone's reduced modulus decreased significantly during the initial 40% of the life fraction, whereas it proceeded slowly during the remaining period. As the size of the residual indentations was about 4 μm in length, the degradation of bone's reduced modulus reflected the accumulation of fatigue damage at smaller scales.
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