Evidence map›Paper›PMID 34204665›Full record

ReviewMicroorganisms2021

MALDI-TOF MS in a Medical Mycology Laboratory: On Stage and Backstage.

Marie-Gladys Robert, Muriel Cornet, Aurélie Hennebique, Tahinamandranto Rasamoelina, Yvan Caspar, Léa Pondérand, Marie Bidart, Harmonie Durand, Marvin Jacquet, Cécile Garnaud and 1 more

Open access · goldAbstract readReview
In one paragraph

Review in Microorganisms, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 1 pooled it
3.8field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 1 synthesis or guideline pooled it, 36 citations in OpenAlex.

  1. Brazilian guidelines for the diagnosis and treatment of candidemia and invasive candidiasis in adults and children.The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases
    Guideline
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. First case of a humanASM case reports · 2026
    Article
  8. Animals : an open access journal from MDPI · 2025
    Review
  9. Review
  10. Article
  11. Review
  12. Article
  13. Review
  14. Journal of fungi (Basel, Switzerland) · 2025
    Article
  15. ISCCM Position Statement on the Management of Invasive Fungal Infections in the Intensive Care Unit.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2024
    Article
  16. Article
  17. Article
  18. A case report ofFrontiers in cellular and infection microbiology · 2024
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 2 countries.

Marie-Gladys RobertCentre National de la Recherche Scientifique, Centre Hospitalo-Universitaire Grenoble Alpes, Institut National de la Santé et de la Recherche Médicale, Institut Pour l'Avancée des Biosciences, University Grenoble Alpes, 38000 Grenoble, France.
Muriel CornetTranslational Innovation in Medicine and Complexity, Centre National de la Recherche Scientifique, Centre Hospitalo-Universitaire Grenoble Alpes, Grenoble Alpes University, 38000 Grenoble, France.
Aurélie HennebiqueTranslational Innovation in Medicine and Complexity, Centre National de la Recherche Scientifique, Centre Hospitalo-Universitaire Grenoble Alpes, Grenoble Alpes University, 38000 Grenoble, France.ORCID 0000-0002-5474-7308
Tahinamandranto RasamoelinaCharles Mérieux Infectiology Center, Campus Universitaire d'Ankatso, Antananarivo 101, Madagascar.
Yvan CasparInstitut de Biologie Structurale, Commissariat à l'Énergie Atomique et aux Énergies Alternatives, Centre National de la Recherche Scientifique, Centre Hospitalo-Universitaire Grenoble Alpes, University Grenoble Alpes, 38000 Grenoble, France.
Léa PondérandInstitut de Biologie Structurale, Commissariat à l'Énergie Atomique et aux Énergies Alternatives, Centre National de la Recherche Scientifique, Centre Hospitalo-Universitaire Grenoble Alpes, University Grenoble Alpes, 38000 Grenoble, France.
Marie BidartClinatec Departement, University Grenoble Alpes, Centre Hospitalo-Universitaire Grenoble Alpes, 38000 Grenoble, France.
Harmonie DurandClinatec Departement, University Grenoble Alpes, Centre Hospitalo-Universitaire Grenoble Alpes, 38000 Grenoble, France.
Marvin JacquetTranslational Innovation in Medicine and Complexity, Centre National de la Recherche Scientifique, Centre Hospitalo-Universitaire Grenoble Alpes, Grenoble Alpes University, 38000 Grenoble, France.ORCID 0000-0002-9890-7908
Cécile GarnaudTranslational Innovation in Medicine and Complexity, Centre National de la Recherche Scientifique, Centre Hospitalo-Universitaire Grenoble Alpes, Grenoble Alpes University, 38000 Grenoble, France.
Danièle MaubonTranslational Innovation in Medicine and Complexity, Centre National de la Recherche Scientifique, Centre Hospitalo-Universitaire Grenoble Alpes, Grenoble Alpes University, 38000 Grenoble, France.ORCID 0000-0002-9080-7638
Centre Hospitalier Universitaire de Grenoble · FRCentre National de la Recherche Scientifique · FRTranslational Innovation in Medicine and Complexity · FRUniversity of Antananarivo · MG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The implementation of MALDI-TOF MS in medical microbiology laboratories has revolutionized practices and significantly reduced turnaround times of identification processes. However, although bacteriology quickly benefited from the contributions of this technique, adjustments were necessary to accommodate the specific characteristics of fungi. MALDI-TOF MS is now an indispensable tool in clinical mycology laboratories, both for the identification of yeasts and filamentous fungi, and other innovative uses are gradually emerging. Based on the practical experience of our medical mycology laboratory, this review will present the current uses of MALDI-TOF MS and the adaptations we implemented, to allow their practical execution in a daily routine. We will also introduce some less mainstream applications, like those for fungemia, or even still under development, as is the case for the determination of sensitivity to antifungal agents or typing methods.

Indexed as

antifungal susceptibility testingdiagnosisfungiMALDI-TOF MSmedical mycologymicroorganism identification

Identifiers

PMID34204665
PMCPMC8231132
OpenAlexW3170049102

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.