Evidence map›Paper›PMID 34204661›Full record

ReviewCells2021

Lymphocytes and Trogocytosis-Mediated Signaling.

Jim Reed, Madison Reichelt, Scott A Wetzel

Open access · goldAbstract readReview
In one paragraph

Review in Cells, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 38 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Frontiers in cellular neuroscience · 2026
    Review
  6. Article
  7. Article
  8. Article
  9. Review
  10. Review
  11. Article
  12. Article
  13. The Biological Significance of Trogocytosis.Results and problems in cell differentiation · 2024
    Article
  14. Review
  15. Review
  16. Article
  17. Clathrin mediates both internalization and vesicular release of triggered T cell receptor at the immunological synapse.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Jim ReedDivision of Biological Sciences, University of Montana, Missoula, MT 59812, USA.
Madison ReicheltDivision of Biological Sciences, University of Montana, Missoula, MT 59812, USA.
Scott A WetzelDivision of Biological Sciences, University of Montana, Missoula, MT 59812, USA.ORCID 0000-0001-6843-4583
University of Montana · USCenter for Environmental Health · US

Funding

Characterizing the contribution of trogocytosis to T Follicular Helper differentiation and humoral immune responsesR15AI147034 · NIAID · UNIVERSITY OF MONTANA · PI WETZEL, SCOTT A · 2020 to 2020
$432k
Determining the role of trogocytosis-mediated signaling on CD4 T cell phenotype and effector functionsR03AI122167 · NIAID · UNIVERSITY OF MONTANA · PI WETZEL, SCOTT A · 2016 to 2017
$145k
NIAID NIH HHS R03 AI122167NIAID NIH HHS R15 AI147034
6 · The paper itself

Abstract

Trogocytosis is the intercellular transfer of membrane and membrane-associated molecules. This underappreciated process has been described in a variety of biological settings including neuronal remodeling, fertilization, viral and bacterial spread, and cancer, but has been most widely studied in cells of the immune system. Trogocytosis is performed by multiple immune cell types, including basophils, macrophages, dendritic cells, neutrophils, natural killer cells, B cells, γδ T cells, and CD4

Indexed as

AnimalsAntigen PresentationCD4-Positive T-LymphocytesHumansLymphocyte ActivationNatural Killer T-CellsSignal Transductionauto-presentationCD4+ T cellscytokinedifferentiationimmune responseimmune synapseintercellular transferintracellular signalingnatural killer cellstrogocytosis

Identifiers

PMID34204661
PMCPMC8231098
OpenAlexW3169972885

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.