Evidence map›Paper›PMID 34204625›Full record

ReviewInternational journal of molecular sciences2021

Histamine: A Bacterial Signal Molecule.

Tino Krell, José A Gavira, Félix Velando, Matilde Fernández, Amalia Roca, Elizabet Monteagudo-Cascales, Miguel A Matilla

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
4.0field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 35 citations in OpenAlex.

  1. Article
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  18. Lung microbiota: implications and interactions in chronic pulmonary diseases.Frontiers in cellular and infection microbiology · 2024
    Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Tino KrellDepartment of Environmental Protection, Estación Experimental del Zaidín, Consejo Superior de Investigaciones Científicas, Prof. Albareda 1, 18008 Granada, Spain.ORCID 0000-0002-9040-3166
José A GaviraLaboratory of Crystallographic Studies, IACT (CSIC-UGR), Avenida de las Palmeras 4, 18100 Armilla, Spain.ORCID 0000-0002-7386-6484
Félix VelandoDepartment of Environmental Protection, Estación Experimental del Zaidín, Consejo Superior de Investigaciones Científicas, Prof. Albareda 1, 18008 Granada, Spain.ORCID 0000-0002-5396-4511
Matilde FernándezDepartment of Microbiology, Facultad de Farmacia, Campus Universitario de Cartuja, Universidad de Granada, 18071 Granada, Spain.ORCID 0000-0002-5832-5161
Amalia RocaDepartment of Microbiology, Facultad de Farmacia, Campus Universitario de Cartuja, Universidad de Granada, 18071 Granada, Spain.
Elizabet Monteagudo-CascalesDepartment of Environmental Protection, Estación Experimental del Zaidín, Consejo Superior de Investigaciones Científicas, Prof. Albareda 1, 18008 Granada, Spain.ORCID 0000-0001-6977-3640
Miguel A MatillaDepartment of Environmental Protection, Estación Experimental del Zaidín, Consejo Superior de Investigaciones Científicas, Prof. Albareda 1, 18008 Granada, Spain.ORCID 0000-0002-8468-9604
Consejo Superior de Investigaciones Científicas · ESUniversidad de Granada · ES

Funding

Consejería de Economía, Conocimiento, Empresas y Universidad, Junta de Andalucía P18-FR-1621Consejo Superior de Investigaciones Científicas PIE-202040I003Ministerio de Ciencia, Innovación y Universidades PID2019-103972GA-I00Ministerio de Economía y Competitividad BIO2016-74875-PMinisterio de Economía y Competitividad BIO2016-76779-P
6 · The paper itself

Abstract

Bacteria have evolved sophisticated signaling mechanisms to coordinate interactions with organisms of other domains, such as plants, animals and human hosts. Several important signal molecules have been identified that are synthesized by members of different domains and that play important roles in inter-domain communication. In this article, we review recent data supporting that histamine is a signal molecule that may play an important role in inter-domain and inter-species communication. Histamine is a key signal molecule in humans, with multiple functions, such as being a neurotransmitter or modulator of immune responses. More recent studies have shown that bacteria have evolved different mechanisms to sense histamine or histamine metabolites. Histamine sensing in the human pathogen

Indexed as

Signal TransductionAnimalsBacteriaHistamineHistamine ReleaseHumansModels, BiologicalModels, MolecularHistaminechemotaxisgut microbiomehistaminehistamine receptorsPseudomonas aeruginosasensingsignal molecule

Identifiers

PMID34204625
PMCPMC8231116
OpenAlexW3167644973

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.