Evidence map›Paper›PMID 34204585›Full record

ArticleInternational journal of molecular sciences2021

Dysregulated Expression of Arterial MicroRNAs and Their Target Gene Networks in Temporal Arteries of Treatment-Naïve Patients with Giant Cell Arteritis.

Tadeja Kuret, Katja Lakota, Saša Čučnik, Vesna Jurčič, Oliver Distler, Žiga Rotar, Alojzija Hočevar, Snežna Sodin-Šemrl, Mojca Frank-Bertoncelj

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 12 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Review
  6. Molecular Research in Cardiovascular Disease.International journal of molecular sciences · 2021
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Tadeja KuretInstitute of Cell Biology, Faculty of Medicine, University of Ljubljana, 1000 Ljubljana, Slovenia.ORCID 0000-0002-4749-594X
Katja LakotaDepartment of Rheumatology, University Medical Centre Ljubljana, 1000 Ljubljana, Slovenia.
Saša ČučnikDepartment of Rheumatology, University Medical Centre Ljubljana, 1000 Ljubljana, Slovenia.
Vesna JurčičInstitute of Pathology, Faculty of Medicine, University of Ljubljana, 1000 Ljubljana, Slovenia.ORCID 0000-0003-1231-5600
Oliver DistlerCenter of Experimental Rheumatology, Department of Rheumatology, University Hospital Zurich, University of Zurich, 8952 Schlieren, Switzerland.
Žiga RotarDepartment of Rheumatology, University Medical Centre Ljubljana, 1000 Ljubljana, Slovenia.
Alojzija HočevarDepartment of Rheumatology, University Medical Centre Ljubljana, 1000 Ljubljana, Slovenia.
Snežna Sodin-ŠemrlDepartment of Rheumatology, University Medical Centre Ljubljana, 1000 Ljubljana, Slovenia.
Mojca Frank-BertonceljCenter of Experimental Rheumatology, Department of Rheumatology, University Hospital Zurich, University of Zurich, 8952 Schlieren, Switzerland.
University of Ljubljana · SIUniversity of Primorska · SIUniversity of Zurich · CH

Funding

Javna Agencija za Raziskovalno Dejavnost RS #P3-0314
6 · The paper itself

Abstract

In this study, we explored expression of microRNA (miR), miR-target genes and matrix remodelling molecules in temporal artery biopsies (TABs) from treatment-naïve patients with giant cell arteritis (GCA,

Indexed as

Gene Expression RegulationGene Regulatory NetworksRNA InterferenceBiomarkersBiopsyDisease SusceptibilityGene Expression ProfilingGiant Cell ArteritisHumansImmunohistochemistryKruppel-Like Factor 4MicroRNAsRNA, MessengerSymptom AssessmentTemporal ArteriesUltrasonographyBiomarkersKLF4 protein, humanKruppel-Like Factor 4MicroRNAsRNA, Messengerarterial remodellingarterial ultrasoundgiant cell arteritismicroRNAmicroRNA-target genestoll-like receptor signalingvision disturbances

Identifiers

PMID34204585
PMCPMC8234166
OpenAlexW3166757775

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.