Evidence map›Paper›PMID 34204572›Full record

ArticleNutrients2021

Effects of a Diet Based on Foods from Symbiotic Agriculture on the Gut Microbiota of Subjects at Risk for Metabolic Syndrome.

Silvia Turroni, Elisabetta Petracci, Valeria Edefonti, Anna M Giudetti, Federica D'Amico, Lisa Paganelli, Giusto Giovannetti, Laura Del Coco, Francesco P Fanizzi, Simone Rampelli and 8 more

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
0.7field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 5 institutions in 1 country.

Silvia TurroniDepartment of Pharmacy and Biotechnology, University of Bologna, via Belmeloro, 6, 40126 Bologna, Italy.ORCID 0000-0003-2345-9482
Elisabetta PetracciBiostatistics and Clinical Trial Unit, Istituto Romagnolo per lo Studio dei Tumori "Dino Amadori"-IRST S.r.l., IRCCS, via P. Maroncelli, 40, 47014 Meldola, Italy.
Valeria EdefontiBranch of Medical Statistics, Biometry, and Epidemiology "G.A. Maccacaro", Department of Clinical Sciences and Community Health, Università degli Studi di Milano, via A. Vanzetti, 5, 20133 Milano, Italy.ORCID 0000-0002-1995-1477
Anna M GiudettiDepartment of Biological and Environmental Sciences and Technologies, University of Salento, via Province of Lecce-Monteroni, 73100 Lecce, Italy.ORCID 0000-0002-9204-040X
Federica D'AmicoDepartment of Pharmacy and Biotechnology, University of Bologna, via Belmeloro, 6, 40126 Bologna, Italy.
Lisa PaganelliDonna Impresa Coldiretti Forlì-Cesena e Rimini, via E. Forlanini, 11, 47121 Forli, Italy.
Giusto GiovannettiCentro Colture Sperimentali, CCS Aosta S.r.l., Frazione Olleyes 9, 11020 Quart, Italy.
Laura Del CocoDepartment of Biological and Environmental Sciences and Technologies, University of Salento, via Province of Lecce-Monteroni, 73100 Lecce, Italy.ORCID 0000-0002-4805-7538
Francesco P FanizziDepartment of Biological and Environmental Sciences and Technologies, University of Salento, via Province of Lecce-Monteroni, 73100 Lecce, Italy.ORCID 0000-0003-3073-5772
Simone RampelliDepartment of Pharmacy and Biotechnology, University of Bologna, via Belmeloro, 6, 40126 Bologna, Italy.ORCID 0000-0002-5655-6695
Debora GuerraDepartment of Medical Oncology, Istituto Romagnolo per lo Studio dei Tumori "Dino Amadori"-IRST S.r.l., IRCCS, via P. Maroncelli, 40, 47014 Meldola, Italy.
Claudia RengucciBioscience Laboratory, Istituto Romagnolo per lo Studio dei Tumori "Dino Amadori"-IRST S.r.l., IRCCS, via P. Maroncelli, 40, 47014 Meldola, Italy.
Jenny BulgarelliImmunotherapy, Cell Therapy and Biobank Unit, Istituto Romagnolo per lo Studio dei Tumori "Dino Amadori"-IRST S.r.l., IRCCS, via P. Maroncelli, 40, 47014 Meldola, Italy.ORCID 0000-0002-6551-0189
Marcella TazzariImmunotherapy, Cell Therapy and Biobank Unit, Istituto Romagnolo per lo Studio dei Tumori "Dino Amadori"-IRST S.r.l., IRCCS, via P. Maroncelli, 40, 47014 Meldola, Italy.
Nicoletta PellegriniDepartment of Agricultural, Food, Environmental and Animal Sciences, Università di Udine, via delle Scienze 206, 33100 Udine, Italy.ORCID 0000-0002-9178-5274
Monica FerraroniBranch of Medical Statistics, Biometry, and Epidemiology "G.A. Maccacaro", Department of Clinical Sciences and Community Health, Università degli Studi di Milano, via A. Vanzetti, 5, 20133 Milano, Italy.ORCID 0000-0002-4542-4996
Oriana NanniBiostatistics and Clinical Trial Unit, Istituto Romagnolo per lo Studio dei Tumori "Dino Amadori"-IRST S.r.l., IRCCS, via P. Maroncelli, 40, 47014 Meldola, Italy.
Patrizia SerraBiostatistics and Clinical Trial Unit, Istituto Romagnolo per lo Studio dei Tumori "Dino Amadori"-IRST S.r.l., IRCCS, via P. Maroncelli, 40, 47014 Meldola, Italy.
Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori · ITUniversity of Bologna · ITUniversity of Salento · ITUniversity of Milan · ITUniversity of Udine · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Diet is a major driver of gut microbiota variation and plays a role in metabolic disorders, including metabolic syndrome (MS). Mycorrhized foods from symbiotic agriculture (SA) exhibit improved nutritional properties, but potential benefits have never been investigated in humans. We conducted a pilot interventional study on 60 adults with ≥ 1 risk factors for MS, of whom 33 consumed SA-derived fresh foods and 27 received probiotics over 30 days, with a 15-day follow-up. Stool, urine and blood were collected over time to explore changes in gut microbiota, metabolome, and biochemical, inflammatory and immunologic parameters; previous dietary habits were investigated through a validated food-frequency questionnaire. The baseline microbiota showed alterations typical of metabolic disorders, mainly an increase in

Indexed as

AgricultureDietGastrointestinal MicrobiomeAdolescentAdultAgedDiet, HealthyFecesFemaleHumansItalyMaleMetabolic SyndromeMetabolomeMiddle AgedPilot Projectsadult volunteersdietary interventiondietary patternsgut microbiotametabolic dysfunctionmetabolic syndromemetabolomepilot studysymbiotic agriculture

Identifiers

PMID34204572
PMCPMC8235411
OpenAlexW3170656861

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.