ReviewToxins2021
Old World Vipers-A Review about Snake Venom Proteomics of Viperinae and Their Variations.
Review in Toxins, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
39 citing papers in PubMed, 80 citations in OpenAlex.
- Immunological Cross-Reactivity and Neutralizing Efficacy of Antivenom Against Five Medically Important Iranian Viper Venoms.Veterinary medicine and science · 2026Article
- Article
- Cardiotoxin from Naja atra Activates the NLRP3/Caspase-1/GSDMD Pyroptosis Pathway to Induce Skin Tissue Injury.PLoS neglected tropical diseases · 2026Article
- Comparative venomics reveals intra, interspecific and ontogenetic changes in the venom composition of Lachesis snakes from Colombia.PLoS neglected tropical diseases · 2026Article
- Upper limb compartment syndrome requiring fasciotomies following aCase reports in plastic surgery & hand surgery · 2026Article
- Unveiling the Evolutionary History of European Vipers and Their Venoms From a Multi-Omic Approach.Molecular ecology · 2025Article
- Comparative Proteomics, Functional Characterization and Immunological Cross-Reactivity Studies on Russell's Viper Venom from Two Distinct Geographical Regions in South India.International journal of molecular sciences · 2025Article
- Venomics of the Arabian saw-scaled viper (Echis coloratus) through transcriptome-guided proteomics and in vitro functional profiling.PLoS neglected tropical diseases · 2025Article
- Preclinical evaluation of the neutralising efficacy of three antivenoms against the venoms of the recently taxonomically partitioned E. ocellatus and E. romani.PLoS neglected tropical diseases · 2025Article
- Article
- The biology and toxinology of blunt-nosed vipers.npj biodiversity · 2025Review
- Metabolomics and proteomics: synergistic tools for understanding snake venom inhibition.Archives of toxicology · 2025Review
- The Versatility of Serine Proteases from BrazilianBiomolecules · 2025Review
- A dose scaling antivenin protocol in treatment of Daboia palaestinae envenomation may reduce morbidity and costs.PloS one · 2025Article
- Article
- The Venom ofVeterinary sciences · 2024Article
- Tiny but Mighty:Toxins · 2024Article
- Comparative venom analysis between melanistic and normally coloured phenotypes of the common adder (Royal Society open science · 2024Article
- Article
- Article
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
Abstract
Fine-tuned by millions of years of evolution, snake venoms have frightened but also fascinated humanity and nowadays they constitute potential resources for drug development, therapeutics and antivenoms. The continuous progress of mass spectrometry techniques and latest advances in proteomics workflows enabled toxinologists to decipher venoms by modern omics technologies, so-called 'venomics'. A tremendous upsurge reporting on snake venom proteomes could be observed. Within this review we focus on the highly venomous and widely distributed subfamily of Viperinae (Serpentes: Viperidae). A detailed public literature database search was performed (2003-2020) and we extensively reviewed all compositional venom studies of the so-called Old-World Vipers. In total, 54 studies resulted in 89 venom proteomes. The Viperinae venoms are dominated by four major, four secondary, six minor and several rare toxin families and peptides, respectively. The multitude of different venomics approaches complicates the comparison of venom composition datasets and therefore we differentiated between non-quantitative and three groups of quantitative workflows. The resulting direct comparisons within these groups show remarkable differences on the intra- and interspecies level across genera with a focus on regional differences. In summary, the present compilation is the first comprehensive up-to-date database on Viperinae venom proteomes and differentiating between analytical methods and workflows.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.