Evidence map›Paper›PMID 34204501›Full record

ArticleVaccines2021

Immune Response to Vaccination against COVID-19 in Breastfeeding Health Workers.

Katarzyna Jakuszko, Katarzyna Kościelska-Kasprzak, Marcelina Żabińska, Dorota Bartoszek, Paweł Poznański, Dagna Rukasz, Renata Kłak, Barbara Królak-Olejnik, Magdalena Krajewska

Open access · goldAbstract read
In one paragraph

Article in Vaccines, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 6 pooled it
8.0field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 6 syntheses or guidelines pooled it, 55 citations in OpenAlex.

  1. Neutralizing antibodies in milk and blood of lactating women vaccinated for SARS-CoV-2: a systematic review.Revista paulista de pediatria : orgao oficial da Sociedade de Pediatria de Sao Paulo · 2024
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  20. COVID-19 disease and vaccination in pregnant and lactating women.American journal of reproductive immunology (New York, N.Y. : 1989) · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Katarzyna JakuszkoDepartment of Nephrology and Transplantation Medicine, Wroclaw Medical University, 50-367 Wroclaw, Poland.
Katarzyna Kościelska-KasprzakDepartment of Nephrology and Transplantation Medicine, Wroclaw Medical University, 50-367 Wroclaw, Poland.ORCID 0000-0002-3216-438X
Marcelina ŻabińskaDepartment of Nephrology and Transplantation Medicine, Wroclaw Medical University, 50-367 Wroclaw, Poland.
Dorota BartoszekDepartment of Nephrology and Transplantation Medicine, Wroclaw Medical University, 50-367 Wroclaw, Poland.
Paweł PoznańskiDepartment of Nephrology and Transplantation Medicine, Wroclaw Medical University, 50-367 Wroclaw, Poland.ORCID 0000-0003-1235-3551
Dagna RukaszDepartment of Nephrology and Transplantation Medicine, Wroclaw Medical University, 50-367 Wroclaw, Poland.
Renata KłakDepartment of Nephrology and Transplantation Medicine, Wroclaw Medical University, 50-367 Wroclaw, Poland.
Barbara Królak-OlejnikDepartment of Neonatology, Wroclaw Medical University, 50-367 Wroclaw, Poland.
Magdalena KrajewskaDepartment of Nephrology and Transplantation Medicine, Wroclaw Medical University, 50-367 Wroclaw, Poland.
Wroclaw Medical University · PL

Funding

The study was financially supported from the subsidy of Ministry of Science and Higher Education for maintenance and development of the research capacity of Wroclaw Medical University. The study was financially supported from the subsidy of Ministry of Science and Higher Education for maintenance and development of the research capacity of Wroclaw Medical University.
6 · The paper itself

Abstract

backgroundInitially, there were no data on the safety of COVID-19 vaccines in lactating women. The aim of our study was to evaluate the immune response to COVID-19 vaccinations in breastfeeding women.

methodsThe study included 32 breastfeeding women who, regardless of the study, had decided to be vaccinated. Maternal serum and breast milk samples were simultaneously collected on days 8 ± 1, 22 ± 2, 29 ± 3, and 43 ± 4 after the first dose of the vaccine. The immune response was assessed by determining the presence of anti-SARS-CoV-2 IgG and IgA.

resultsThe breast milk IgG level was detectable (6.50 ± 6.74, median 4.7, and maximum 34.2 BAU/mL) and highly correlated to serum IgG level (r

conclusionThe immune response to the vaccination against SARS-CoV-2 is strongest 7 ± 3 days after the second dose of the vaccine. Lactating mothers breastfeeding their children after vaccination against SARS-CoV-2 may transfer antibodies to their infant.

Indexed as

anti-SARS-CoV-2 antibodiesbreastfeedingbreast milkCOVID-19lactationmRNA vaccinevaccination

Identifiers

PMID34204501
PMCPMC8235492
OpenAlexW3170670647

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.