Evidence map›Paper›PMID 34204498›Full record

ArticleDiagnostics (Basel, Switzerland)2021

A Randomized Comparison of Delivered Energy in Cardioversion of Atrial Fibrillation: Biphasic Truncated Exponential Versus Pulsed Biphasic Waveforms.

Elina Trendafilova, Elena Dimitrova, Jean-Philippe Didon, Vessela Krasteva

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05316753 (Comparison of Biphasic Truncated Exponential and Pulsed Waveforms for Cardioversion of Atrial Fibrillation-High Energy Escalation Strategy and Introduction to Manual Pressure Application), which is not on this map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
0.3field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05316753 naunknown statusnot on this mapstarted 2022, after this paper: background citation

Comparison of Biphasic Truncated Exponential and Pulsed Waveforms for Cardioversion of Atrial Fibrillation-High Energy Escalation Strategy and Introduction to Manual Pressure Application

TypeinterventionalSponsorUniversity National Heart HospitalRan2022 to 2024Enrolled94ConditionsAtrial FibrillationArmsCardioversion with a pulsed biphasic waveform, Cardioversion with a biphasic truncated exponential waveform
3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it, 3 citations in OpenAlex.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

Elina TrendafilovaIntensive Cardiology Care Unit, Cardiology Clinic, National Cardiology Hospital, 65 Konyovitza Str., 1309 Sofia, Bulgaria.ORCID 0000-0002-7175-4438
Elena DimitrovaIntensive Cardiology Care Unit, Cardiology Clinic, National Cardiology Hospital, 65 Konyovitza Str., 1309 Sofia, Bulgaria.
Jean-Philippe DidonSchiller Médical SAS, 4 rue L. Pasteur, F-67160 Wissembourg, France.
Vessela KrastevaInstitute of Biophysics and Biomedical Engineering, Bulgarian Academy of Sciences, Acad. G. Bonchev Str. Bl 105, 1113 Sofia, Bulgaria.ORCID 0000-0001-5385-2109
National Heart Hospital · BGBulgarian Academy of Sciences · BGSchiller (France) · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A few randomized trials have compared impedance-compensated biphasic defibrillators in clinical use. We aim to compare pulsed biphasic (PB) and biphasic truncated exponential (BTE) waveforms in a non-inferiority cardioversion (CVS) study. This was a prospective monocentric randomized clinical trial. Eligible patients admitted for elective CVS of atrial fibrillation (AF) between February 2019 and March 2020 were alternately randomized to treatment with either a PB defibrillator (DEFIGARD TOUCH7, Schiller Médical, Wissembourg, France) or a BTE high-energy (BTE-HE) defibrillator (LIFEPAK15, Physio-Control Inc., Redmond, WA, USA). Fixed-energy protocol (200-200-200 J) was administered. CVS success was accepted if sinus rhythm was restored at 1 min post-shock. The study design considered non-inferiority testing of the primary outcome: cumulative delivered energy (CDE). Seventy-three out of 78 randomized patients received allocated intervention: 38 BTE-HE (52%), 35 PB (48%). Baseline characteristics were well-balanced between groups (

Indexed as

atrial fibrillationbiphasic waveform defibrillationcardioversiondelivered energyefficacyhigh-sensitivity troponinsafety

Identifiers

PMID34204498
PMCPMC8235401
OpenAlexW3166801738

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.