Evidence map›Paper›PMID 34204438›Full record

ArticleInternational journal of molecular sciences2021

2-O-Methylhonokiol Suppresses HCV Replication via TRAF6-Mediated NF-kB Activation.

Suyun Jeong, Young-Seok Lee, Kiyoon Kim, Ji-Su Yoon, Sungsoo Kim, Joohun Ha, Insug Kang, Wonchae Choe

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.8field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Suyun JeongDepartment of Biomedical Science, Graduate School, Kyung Hee University, Seoul 02447, Korea.ORCID 0000-0002-7538-880X
Young-Seok LeeDepartment of Biomedical Science, Graduate School, Kyung Hee University, Seoul 02447, Korea.ORCID 0000-0001-9560-5640
Kiyoon KimDepartment of Biochemistry and Molecular Biology, School of Medicine, Kyung Hee University, Seoul 02447, Korea.
Ji-Su YoonDepartment of Biomedical Science, Graduate School, Kyung Hee University, Seoul 02447, Korea.
Sungsoo KimDepartment of Biomedical Science, Graduate School, Kyung Hee University, Seoul 02447, Korea.
Joohun HaDepartment of Biomedical Science, Graduate School, Kyung Hee University, Seoul 02447, Korea.
Insug KangDepartment of Biomedical Science, Graduate School, Kyung Hee University, Seoul 02447, Korea.ORCID 0000-0001-7117-1008
Wonchae ChoeDepartment of Biomedical Science, Graduate School, Kyung Hee University, Seoul 02447, Korea.ORCID 0000-0001-5764-9482
Kyung Hee University · KR

Funding

National Research Foundation of Korea 2018R1A6A1A030525124National Research Foundation of Korea NRF-2017R1A2B2002289
6 · The paper itself

Abstract

Hepatitis C virus (HCV) is associated with various liver diseases. Chronic HCV infection is characterized by an abnormal host immune response. Therefore, it is speculated that to suppress HCV, a well-regulated host immune response is necessary. 2-O-methylhonokiol was identified by the screening of anti-HCV compounds using

Indexed as

Host-Pathogen InteractionsVirus ReplicationB-LymphocytesCell LineCells, CulturedHepacivirusHepatitis CHumansImmunity, InnateModels, BiologicalMolecular StructureNF-kappa BTNF Receptor-Associated Factor 6NF-kappa BTNF Receptor-Associated Factor 62-O-methylhonokiolhepatitis C virusinnate immune responsenuclear factor kappa-light-chain-enhancer of activated B cells

Identifiers

PMID34204438
PMCPMC8234778
OpenAlexW3169672170

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.