Evidence map›Paper›PMID 34204263›Full record

ArticleMicroorganisms2021

In Vitro Selection of Probiotics, Prebiotics, and Antioxidants to Develop an Innovative Synbiotic (NatuREN G) and Testing Its Effect in Reducing Uremic Toxins in Fecal Batches from CKD Patients.

Mirco Vacca, Giuseppe Celano, Marcello Salvatore Lenucci, Sergio Fontana, Flavia Maria la Forgia, Fabio Minervini, Aurelia Scarano, Angelo Santino, Giuseppe Dalfino, Loreto Gesualdo and 1 more

Open access · goldAbstract read
In one paragraph

Article in Microorganisms, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 33 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. UnravelingFrontiers in pharmacology · 2025
    Review
  6. Review
  7. Review
  8. Article
  9. Article
  10. Review
  11. Frontiers in nutrition · 2023
    Article
  12. Microorganisms · 2022
    Article
  13. Article
  14. Review
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 1 country.

Mirco VaccaDepartment of Soil Plant and Food Sciences, University of Bari, 70126 Bari, Italy.ORCID 0000-0003-0813-169X
Giuseppe CelanoDepartment of Soil Plant and Food Sciences, University of Bari, 70126 Bari, Italy.ORCID 0000-0002-3805-7681
Marcello Salvatore LenucciDepartment of Biological and Environmental Science and Technologies, University of Salento, 73100 Lecce, Italy.ORCID 0000-0002-6493-9549
Sergio FontanaFarmalabor srl, 76012 Canosa di Puglia, Italy.
Flavia Maria la ForgiaFarmalabor srl, 76012 Canosa di Puglia, Italy.
Fabio MinerviniDepartment of Soil Plant and Food Sciences, University of Bari, 70126 Bari, Italy.ORCID 0000-0003-1062-9374
Aurelia ScaranoUnit of Lecce, Institute of Sciences of Food Production C.N.R., 73100 Lecce, Italy.ORCID 0000-0002-8169-1514
Angelo SantinoUnit of Lecce, Institute of Sciences of Food Production C.N.R., 73100 Lecce, Italy.ORCID 0000-0002-3348-0747
Giuseppe DalfinoNational Institute of Gastroenterology "S. de Bellis" Research Hospital, 70013 Castellana Grotte, Italy.
Loreto GesualdoNephrology, Dialysis and Transplantation Unit, Department of Emergency and Organ Transplantation, "Aldo Moro" University, 70124 Bari, Italy.
Maria De AngelisDepartment of Soil Plant and Food Sciences, University of Bari, 70126 Bari, Italy.ORCID 0000-0002-2010-884X
University of Bari Aldo Moro · ITInstitute of Sciences of Food Production · ITGastroenterology Hospital "Saverio de Bellis" · ITUniversity of Salento · IT

Funding

Regione Puglia XUANRO4
6 · The paper itself

Abstract

We aimed to develop an innovative synbiotic formulation for use in reducing dysbiosis, uremic toxins (e.g.,

Indexed as

antioxidantschronic kidney diseasefecal batchesmicrobiotaprebioticsprobioticssynbiotic

Identifiers

PMID34204263
PMCPMC8235484
OpenAlexW3172648414

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.