ReviewBiomolecules2021
Effect of Polyploidy Induction on Natural Metabolite Production in Medicinal Plants.
Review in Biomolecules, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
29 citing papers in PubMed, 101 citations in OpenAlex.
- The Convergence of Biotechnological Strategies in Medicinal Plants: From Individual Approaches Toward an Integrated Systems Framework.International journal of molecular sciences · 2026Review
- Polyploidy: A macromutational force pushing bioeconomic developments.Proceedings of the National Academy of Sciences of the United States of America · 2026Review
- Polyploidy and plant resilience to environmental stresses: Molecular mechanisms and future applications.Plant communications · 2026Review
- Mutagenic and physiological impacts of colchicine on growth, flowering behavior, and ISSR-based genetic variability in Calendula officinalis L.BMC plant biology · 2026Article
- The impact of genome duplication on agronomically valuable traits in Ribes nigrum L.: a morpho-anatomical, physiological and cytogenetic evaluation.BMC plant biology · 2026Article
- Distinct metabolic signatures of ploidy and cold storage in blueberry fruit revealed by integrative metabolomics and machine learning.Food chemistry: X · 2026Article
- Adaptive Strategies Mediating the Diversification of Alpine Plants: The Case of the Himalayan Blue Poppy (Plants (Basel, Switzerland) · 2025Article
- Evaluation of in vitro-geranium (Pelargonium graveolens) plants affected by irradiation and chemical mutagens.BMC plant biology · 2025Article
- Colchicine-Induced Polyploidization Influences the Morphological, Physiological, and Biochemical Characteristics ofPlants (Basel, Switzerland) · 2025Article
- Efficient induction of tetraploids via adventitious bud regeneration and subsequent phenotypic variation in Acacia melanoxylon.Plant methods · 2025Article
- Fungal Endophytes: An Insight into Diversity, Stress Tolerance, Biocontrol and Plant Growth-Promoting Potentials.Current microbiology · 2025Review
- In vitro synthetic polyploidization and enhancement of anticancer compounds in Catharanthus Roseus (L.) G. Don important cultivars.Scientific reports · 2025Article
- Machine Learning-Aided Optimization of In Vitro Tetraploid Induction in Cannabis.International journal of molecular sciences · 2025Article
- Oryzalin-induced polyploidy inFrontiers in plant science · 2025Article
- Comparative assessment of morphological, cytological, and photosynthetic characteristics of the induced octoploid and its tetraploid counterpart of Celosia argentea L.BMC plant biology · 2024Article
- Biological Properties of Recently Described Wild BrambleFoods (Basel, Switzerland) · 2024Article
- Comparative Analysis of Root Phenolic Profiles and Antioxidant Activity of Five Native and InvasivePlants (Basel, Switzerland) · 2024Article
- Promising approaches for simultaneous enhancement of medicinally significant benzylisoquinoline alkaloids in opium poppy.Frontiers in plant science · 2024Review
- Transcriptomic and metabolomic analyses reveal the differential accumulation of phenylpropanoids and terpenoids in hemp autotetraploid and its diploid progenitor.BMC plant biology · 2023Article
- Metabolic Effects of Elicitors on the Biosynthesis of Tropane Alkaloids in Medicinal Plants.Plants (Basel, Switzerland) · 2023Review
Corrections and comments
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Authors and funding
6 authors at 4 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Polyploidy plays an important role in plant diversification and speciation. The ploidy level of plants is associated with morphological and biochemical characteristics, and its modification has been used as a strategy to alter the quantitative and qualitative patterns of secondary metabolite production in different medicinal plants. Polyploidization can be induced by many anti-mitotic agents, among which colchicine, oryzalin, and trifluralin are the most common. Other variables involved in the induction process include the culture media, explant types, and exposure times. Due to the effects of polyploidization on plant growth and development, chromosome doubling has been applied in plant breeding to increase the levels of target compounds and improve morphological characteristics. Prompted by the importance of herbal medicines and the increasing demand for drugs based on plant secondary metabolites, this review presents an overview of how polyploidy can be used to enhance metabolite production in medicinal plants.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.