Evidence map›Paper›PMID 34204186›Full record

ArticleCancers2021

HCC in the Era of Direct-Acting Antiviral Agents (DAAs): Surgical and Other Curative or Palliative Strategies in the Elderly.

Stefania Brozzetti, Marsia Tancredi, Simone Bini, Chiara De Lucia, Jessica Antimi, Chiara D'Alterio, Giuseppe Maria De Sanctis, Caterina Furlan, Vittoria Carolina Malpassuti, Pierleone Lucatelli and 4 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cancers, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 3 institutions in 1 country.

Stefania BrozzettiDepartment of Surgery "Pietro Valdoni", Policlinico Umberto I, University of Rome La Sapienza, 00161 Rome, Italy.
Marsia TancrediDepartment of Surgery "Pietro Valdoni", Policlinico Umberto I, University of Rome La Sapienza, 00161 Rome, Italy.
Simone BiniDepartment of Translational and Precision Medicine, Policlinico Umberto I, University of Rome La Sapienza, 00161 Rome, Italy.ORCID 0000-0002-1006-4636
Chiara De LuciaDepartment of Surgery "Pietro Valdoni", Policlinico Umberto I, University of Rome La Sapienza, 00161 Rome, Italy.
Jessica AntimiDepartment of Surgery "Pietro Valdoni", Policlinico Umberto I, University of Rome La Sapienza, 00161 Rome, Italy.ORCID 0000-0003-0035-0564
Chiara D'AlterioDepartment of Surgery "Pietro Valdoni", Policlinico Umberto I, University of Rome La Sapienza, 00161 Rome, Italy.ORCID 0000-0003-0165-7306
Giuseppe Maria De SanctisDepartment of Tropical and Infectious Diseases, Policlinico Umberto I, University of Rome La Sapienza, 00161 Rome, Italy.
Caterina FurlanDepartment of Tropical and Infectious Diseases, Policlinico Umberto I, University of Rome La Sapienza, 00161 Rome, Italy.
Vittoria Carolina MalpassutiDepartment of Statistical Sciences, University of Rome La Sapienza, 00161 Rome, Italy.ORCID 0000-0001-7377-4785
Pierleone LucatelliDepartment of Radiological Sciences Policlinico Umberto I, University of Rome La Sapienza, 00161 Rome, Italy.ORCID 0000-0002-7448-1404
Michele Di MartinoDepartment of Radiological Sciences Policlinico Umberto I, University of Rome La Sapienza, 00161 Rome, Italy.
Mario BezziDepartment of Radiological Sciences Policlinico Umberto I, University of Rome La Sapienza, 00161 Rome, Italy.
Antonio CiardiDepartment of Radiological, Oncological, Pathological Sciences, Policlinico Umberto I, Sapienza University of Rome, 00161 Rome, Italy.
Rosa Maria PascaleDepartment of Medical, Surgery and Experimental Sciences, Division of Experimental Pathology and Oncology, University of Sassari, 07100 Sassari, Italy.ORCID 0000-0001-7612-3646
Policlinico Umberto I · ITSapienza University of Rome · ITUniversity of Sassari · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hepatocellular carcinoma (HCC) accounts for 75-85% of primary liver malignancies, and elderlies have the highest incidence rates. Direct-acting antiviral agents (DAAs) have shown satisfying results in terms of HCV sustained viral response (SVR). However, data regarding HCC risk post-DAA-SVR is still conflicting. This study aims to consider HCC onset in moderate underlying liver disease. We conducted a retrospective study on 227 chronically infected patients (cHCV), treated with DAAs. Patients were divided into three groups: "

Indexed as

DAAHCCHCC recurrenceHCVhepatitis C virushepatocellular carcinomalocoregional therapysurgery

Identifiers

PMID34204186
PMCPMC8235445
OpenAlexW3168666241

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.