Evidence map›Paper›PMID 34204184›Full record

ArticleJournal of clinical medicine2021

Differentiation of Idiopathic Pulmonary Fibrosis from Connective Tissue Disease-Related Interstitial Lung Disease Using Quantitative Imaging.

Jonathan H Chung, Ayodeji Adegunsoye, Brenna Cannon, Rekha Vij, Justin M Oldham, Christopher King, Steven M Montner, Prahasit Thirkateh, Scott Barnett, Ronald Karwoski and 3 more

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 6 institutions in 1 country.

Jonathan H ChungDepartment of Radiology, The University of Chicago Medicine, Chicago, IL 60637, USA.
Ayodeji AdegunsoyeDepartment of Medicine, The University of Chicago Medicine, Chicago, IL 60637, USA.
Brenna CannonInova Advanced Lung Disease and Transplant Program, Inova Fairfax Hospital, Falls Church, VA 22042, USA.
Rekha VijDepartment of Medicine, The University of Chicago Medicine, Chicago, IL 60637, USA.
Justin M OldhamDepartment of Medicine, The University of California Davis, Sacramento, CA 95616, USA.
Christopher KingAdvanced Lung Disease and Transplant Clinic, Inova Fairfax Hospital, Falls Church, VA 22042, USA.
Steven M MontnerDepartment of Radiology, The University of Chicago Medicine, Chicago, IL 60637, USA.
Prahasit ThirkatehChicago Medical School at Rosalind Franklin University of Medicine and Science, North Chicago, IL 60064, USA.
Scott BarnettInova Heart and Vascular Institute, Inova Fairfax Hospital, Falls Church, VA 22042, USA.
Ronald KarwoskiDepartment of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, MN 55902, USA.
Brian J BartholmaiDepartment of Radiology, Mayo Clinic, Rochester, MN 55902, USA.ORCID 0000-0001-7834-6579
Mary StrekDepartment of Medicine, The University of Chicago Medicine, Chicago, IL 60637, USA.
Steven D NathanInova Heart and Vascular Institute, Inova Fairfax Hospital, Falls Church, VA 22042, USA.
University of Chicago · USInova Fairfax Hospital · USMayo Clinic · USMayo Clinic in Florida · USRosalind Franklin University of Medicine and Science · USUniversity of California, Davis · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A usual interstitial pneumonia (UIP) imaging pattern can be seen in both idiopathic pulmonary fibrosis (IPF) and connective tissue disease-related interstitial lung disease (CTD-ILD). The purpose of this multicenter study was to assess whether quantitative imaging data differ between IPF and CTD-ILD in the setting of UIP. Patients evaluated at two medical centers with CTD-ILD or IPF and a UIP pattern on CT or pathology served as derivation and validation cohorts. Chest CT data were quantitatively analyzed including total volumes of honeycombing, reticulation, ground-glass opacity, normal lung, and vessel related structures (VRS). VRS was compared with forced vital capacity percent predicted (FVC%) and percent predicted diffusing capacity of the lungs for carbon monoxide (DLCO%). There were 296 subjects in total, with 40 CTD-ILD and 85 IPF subjects in the derivation cohort, and 62 CTD-ILD and 109 IPF subjects in the validation cohort. VRS was greater in IPF across the cohorts on univariate (

Indexed as

computer-assistedconnective tissue diseaseidiopathic pulmonary fibrosisimage interpretationmultidetector computed tomographyusual interstitial pneumonia

Identifiers

PMID34204184
PMCPMC8233999
OpenAlexW3171871840

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.