Evidence map›Paper›PMID 34204176›Full record

ReviewInternational journal of molecular sciences2021

Molecular Interactions between Dietary Lipids and Bone Tissue during Aging.

Jose M Romero-Márquez, Alfonso Varela-López, María D Navarro-Hortal, Alberto Badillo-Carrasco, Tamara Y Forbes-Hernández, Francesca Giampieri, Irma Domínguez, Lorena Madrigal, Maurizio Battino, José L Quiles

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
1.4field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Factors associated with frailty and the effect of frailty on postoperative outcomes in older adults with hip fracture.Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES · 2025
    Article
  6. Article
  7. Article
  8. Article
  9. Nutraceuticals in osteoporosis prevention.Frontiers in nutrition · 2024
    Review
  10. Review
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 5 countries.

Jose M Romero-MárquezDepartment of Physiology, Institute of Nutrition and Food Technology ''José Mataix", Biomedical Research Centre, University of Granada, Armilla, Avda. del Conocimiento s.n., 18100 Armilla, Spain.ORCID 0000-0001-7033-969X
Alfonso Varela-LópezDepartment of Physiology, Institute of Nutrition and Food Technology ''José Mataix", Biomedical Research Centre, University of Granada, Armilla, Avda. del Conocimiento s.n., 18100 Armilla, Spain.ORCID 0000-0002-0504-5086
María D Navarro-HortalDepartment of Physiology, Institute of Nutrition and Food Technology ''José Mataix", Biomedical Research Centre, University of Granada, Armilla, Avda. del Conocimiento s.n., 18100 Armilla, Spain.
Alberto Badillo-CarrascoDepartment of Physiology, Institute of Nutrition and Food Technology ''José Mataix", Biomedical Research Centre, University of Granada, Armilla, Avda. del Conocimiento s.n., 18100 Armilla, Spain.
Tamara Y Forbes-HernándezNutrition and Food Science Group, Department of Analytical and Food Chemistry, CITACA, CACTI, University of Vigo, 36310 Vigo, Spain.
Francesca GiampieriDepartment of Clinical Sicences, Università Politecnica delle Marche, 60131 Ancona, Italy.ORCID 0000-0002-8151-9132
Irma DomínguezResearch Group on Foods, Nutritional Biochemistry and Health, Universidad Europea del Atlántico, Isabel Torres 21, 39011 Santander, Spain.ORCID 0000-0001-7261-5205
Lorena MadrigalUniversidad Internacional Iberoamericana, Calle 15 Num. 36, Entre 10 y 12 IMI III, Campeche 24560, Mexico.
Maurizio BattinoDepartment of Clinical Sicences, Università Politecnica delle Marche, 60131 Ancona, Italy.ORCID 0000-0002-7250-1782
José L QuilesDepartment of Physiology, Institute of Nutrition and Food Technology ''José Mataix", Biomedical Research Centre, University of Granada, Armilla, Avda. del Conocimiento s.n., 18100 Armilla, Spain.ORCID 0000-0002-9048-9086
Universidad de Granada · ESIbero American University · MXJiangsu University · CNMarche Polytechnic University · ITUniversidade de Vigo · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Age-related bone disorders such as osteoporosis or osteoarthritis are a major public health problem due to the functional disability for millions of people worldwide. Furthermore, fractures are associated with a higher degree of morbidity and mortality in the long term, which generates greater financial and health costs. As the world population becomes older, the incidence of this type of disease increases and this effect seems notably greater in those countries that present a more westernized lifestyle. Thus, increased efforts are directed toward reducing risks that need to focus not only on the prevention of bone diseases, but also on the treatment of persons already afflicted. Evidence is accumulating that dietary lipids play an important role in bone health which results relevant to develop effective interventions for prevent bone diseases or alterations, especially in the elderly segment of the population. This review focuses on evidence about the effects of dietary lipids on bone health and describes possible mechanisms to explain how lipids act on bone metabolism during aging. Little work, however, has been accomplished in humans, so this is a challenge for future research.

Indexed as

AgingAnimalsAutophagyBiomarkersBone and BonesBone RemodelingDietDietary FatsGenomic InstabilityHormonesHumansOsteitisOxidative StressBiomarkersDietary FatsHormonesdietary lipidshallmarks of agingoxidative stresssaturated fat diet

Identifiers

PMID34204176
PMCPMC8233828
OpenAlexW3170773575

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.