Evidence map›Paper›PMID 34204112›Full record

ArticlePathogens (Basel, Switzerland)2021

Transcription Factor HSF1 Suppresses the Expression of Surfactant Protein D in Cells Infected with

Sung-Su Kim, Kwang-Soo Shin

Open access · goldAbstract read
In one paragraph

Article in Pathogens (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Sung-Su KimDepartment of Biomedical Laboratory Science, Daejeon University, Daejeon 34520, Korea.ORCID 0000-0002-7908-423X
Kwang-Soo ShinDepartment of Microbiology, Graduate School, Daejeon University, Daejeon 34520, Korea.ORCID 0000-0001-7762-9593
Daejeon University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aspergillosis is a life-threatening disease in patients with compromised immune systems. The process of fungal invasion is an important step during host cell infection. We investigated the transcription factor and promoter region of SFTPD, which is activated during the infection process in conidia-treated cells. To investigate the promoter activity of SFTPD in fungal-infected cells, we cloned various lengths of the promoter region (-1000 to +1) of SFTPD and examined its activity in A549 cells treated with

Indexed as

aspergillosisAspergillus fumigatusHSF1surfactant protein D

Identifiers

PMID34204112
PMCPMC8229574
OpenAlexW3171597608

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.