Evidence map›Paper›PMID 34204086›Full record

ArticleBrain sciences2021

The Impact of Hypertension and Atrial Fibrillation on Cognitive Decline and Subclinical Atherosclerosis.

Marius Militaru, Ciprian Rachieru, Daniel Florin Lighezan, Anda Gabriela Militaru

Open access · goldAbstract read
In one paragraph

Article in Brain sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Marius MilitaruDepartment of Neuroscience, Discipline of Neurology, Victor Babes University of Medicine and Pharmacy Timisoara, Municipal Emergency Hospital Timisoara, Piaţa Eftimie Murgu Nr. 2, 300041 Timisoara, Romania.
Ciprian RachieruDepartment of Internal Medicine I, Discipline of Medical Semiology I, Victor Babes University of Medicine and Pharmacy Timisoara, Municipal Emergency Hospital Timisoara, Str. Ghe. Dima 5, 300079 Timisoara, Romania.
Daniel Florin LighezanDepartment of Internal Medicine I, Discipline of Medical Semiology I, Victor Babes University of Medicine and Pharmacy Timisoara, Municipal Emergency Hospital Timisoara, Str. Ghe. Dima 5, 300079 Timisoara, Romania.
Anda Gabriela MilitaruDepartment of Internal Medicine I, Discipline of Medical Semiology I, Victor Babes University of Medicine and Pharmacy Timisoara, Municipal Emergency Hospital Timisoara, Str. Ghe. Dima 5, 300079 Timisoara, Romania.
Victor Babeș University of Medicine and Pharmacy Timișoara · RO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAssessment of cognitive impairment and the presence of subclinical atherosclerosis are very important especially in patients with cardiovascular risk factors.

methodsWe included 155 hypertensive patients (84 with AF versus 71 without AF) to identify the premature cognitive impairment, the earliest signs of subclinical atherosclerosis and onset of myocardial dysfunction and to evaluate the type of anticoagulation used, the importance of CHA₂DS₂-VASc score (</>3), age (</>65 years) in hypertensive patients with AF.

resultsMini-Mental State Examination (MMSE), Montreal Cognitive Assessment Scale (MoCA), Left Ventricular Ejection Fraction (LVEF) were significantly decreased, and Activities of Daily Living Score (ADL), Geriatric Depression Scale(GDS-15), and intima-media thickness (IMT) were significantly increased in hypertensive patients with AF vs. without AF (

conclusionsCognitive impairment is encountered in hypertensive patients having AF. Our conclusions suggest a direct link between cognitive impairment, depression, hypertension, AF, age, CHA₂DS₂-VASc score, type of anticoagulants used, LVEF, cognitive parameters, and IMT. We acknowledge the importance of identifying and preventing cognitive changes.

Indexed as

atrial fibrillationcognitive impairmenthypertensionmemory testssubclinical atherosclerosis

Identifiers

PMID34204086
PMCPMC8228320
OpenAlexW3168240332

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.