Evidence map›Paper›PMID 34204019›Full record

ArticleBiomolecules2021

Exploring the Connection between

Raffaella Franciotti, Pamela Pignatelli, Claudia Carrarini, Federica Maria Romei, Martina Mastrippolito, Antonella Gentile, Rosa Mancinelli, Stefania Fulle, Adriano Piattelli, Marco Onofrj and 1 more

Open access · goldAbstract read
In one paragraph

Article in Biomolecules, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 1 pooled it
3.8field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 1 synthesis or guideline pooled it, 36 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Review
  5. Alpha rhythm and Alzheimer's disease: Has Hans Berger's dream come true?Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology · 2025
    Article
  6. Review
  7. Frontiers in microbiology · 2025
    Article
  8. Review
  9. Article
  10. The Immune System Response toMicroorganisms · 2023
    Article
  11. Review
  12. Article
  13. Article
  14. OralBiomedicines · 2022
    Article
  15. The Mechanistic Pathways of Periodontal Pathogens Entering the Brain: The Potential Role ofInternational journal of environmental research and public health · 2022
    Review
  16. Review
  17. Review
  18. Frontiers in cellular and infection microbiology · 2022
    Article
  19. Review
  20. Periodontitis and Neuropathic Diseases: A Literature Review.Journal of International Society of Preventive & Community Dentistry
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Raffaella FranciottiDepartment of Neuroscience, Imaging and Clinical Sciences, "G. d'Annunzio" University of Chieti-Pescara, 66013 Chieti, Italy.ORCID 0000-0002-8819-1061
Pamela PignatelliDepartment of Medical, Oral and Biotechnological Sciences, "G. d'Annunzio" University of Chieti-Pescara, 66013 Chieti, Italy.ORCID 0000-0002-3023-7143
Claudia CarrariniDepartment of Neuroscience, Imaging and Clinical Sciences, "G. d'Annunzio" University of Chieti-Pescara, 66013 Chieti, Italy.
Federica Maria RomeiDepartment of Medical, Oral and Biotechnological Sciences, "G. d'Annunzio" University of Chieti-Pescara, 66013 Chieti, Italy.
Martina MastrippolitoDepartment of Medical, Oral and Biotechnological Sciences, "G. d'Annunzio" University of Chieti-Pescara, 66013 Chieti, Italy.
Antonella GentileDepartment of Medical, Oral and Biotechnological Sciences, "G. d'Annunzio" University of Chieti-Pescara, 66013 Chieti, Italy.
Rosa MancinelliDepartment of Neuroscience, Imaging and Clinical Sciences, "G. d'Annunzio" University of Chieti-Pescara, 66013 Chieti, Italy.
Stefania FulleDepartment of Neuroscience, Imaging and Clinical Sciences, "G. d'Annunzio" University of Chieti-Pescara, 66013 Chieti, Italy.ORCID 0000-0003-4557-9127
Adriano PiattelliDepartment of Medical, Oral and Biotechnological Sciences, "G. d'Annunzio" University of Chieti-Pescara, 66013 Chieti, Italy.
Marco OnofrjDepartment of Neuroscience, Imaging and Clinical Sciences, "G. d'Annunzio" University of Chieti-Pescara, 66013 Chieti, Italy.
Maria Cristina CuriaDepartment of Medical, Oral and Biotechnological Sciences, "G. d'Annunzio" University of Chieti-Pescara, 66013 Chieti, Italy.ORCID 0000-0003-4979-887X
University of Chieti-Pescara · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recent studies support the hypothesis that microbes can seed some Alzheimer's disease (AD) cases, leading to inflammation and overproduction of amyloid peptides.

Indexed as

AgedAged, 80 and overAntibodies, BacterialBacteroidaceae InfectionsBiomarkersCohort StudiesFemaleHumansMaleMiddle AgedMouthNeurodegenerative DiseasesPilot ProjectsPorphyromonas gingivalisAntibodies, BacterialBiomarkersantibodygenomic DNAneurodegenerative diseaseneurological diseaseoral bacteriaperiodontitisPorphyromonas gingivalis

Identifiers

PMID34204019
PMCPMC8229521
OpenAlexW3170868603

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.