Evidence map›Paper›PMID 34203999›Full record

ReviewNutrients2021

A Review on Antifungal Efficiency of Plant Extracts Entrenched Polysaccharide-Based Nanohydrogels.

Navkiranjeet Kaur, Aarti Bains, Ravinder Kaushik, Sanju B Dhull, Fogarasi Melinda, Prince Chawla

Abstract readReview
In one paragraph

Review in Nutrients, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Review
  6. Review
  7. Article
  8. Bioactive polysaccharides fromFood science & nutrition · 2024
    Review
  9. The Emergence ofMini reviews in medicinal chemistry · 2024
    Review
  10. Article
  11. Review
  12. Cellulose Nanocrystal (CNC) Gels: A Review.Gels (Basel, Switzerland) · 2023
    Review
  13. Exploring the Potential of Extracts fromPharmaceuticals (Basel, Switzerland) · 2023
    Article
  14. Green extraction ofFrontiers in chemistry · 2023
    Article
  15. Review
  16. Article
  17. Article
  18. Journal of fungi (Basel, Switzerland) · 2022
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Navkiranjeet KaurDepartment of Food Technology and Nutrition, Lovely Professional University, Phagwara 144411, Punjab, India.
Aarti BainsDepartment of Biotechnology, Chandigarh Group of Colleges Landran, Mohali 140307, Punjab, India.
Ravinder KaushikSchool of Health Sciences, University of Petroleum and Energy Studies, Dehradun 248007, Uttrakhand, India.
Sanju B DhullDepartment of Food Science and Technology, Chaudhary Devi Lal University, Sirsa 125055, Haryana, India.
Fogarasi MelindaDepartment of Food Engineering, University of Agricultural Sciences and Veterinary Medicine of Cluj-Napoca, Calea Mănăstur 3-5, 400372 Cluj-Napoca, Romania.ORCID 0000-0002-9561-1183
Prince ChawlaDepartment of Food Technology and Nutrition, Lovely Professional University, Phagwara 144411, Punjab, India.ORCID 0000-0002-2383-7925

Funding

This work was supported by a grant from the Romanian Ministry of Education and Research, CNCS - UEFISCDI, PN-III-P1-1.1-PD-2019-0475, within PNCDI III
6 · The paper itself

Abstract

Human skin acts as a physical barrier; however, sometimes the skin gets infected by fungi, which becomes more severe if the infection occurs on the third layer of the skin. Azole derivative-based antifungal creams, liquids, or sprays are available to treat fungal infections; however, these formulations show various side effects on the application site. Over the past few years, herbal extracts and various essential oils have shown effective antifungal activity. Additionally, autoxidation and epimerization are significant problems with the direct use of herbal extracts. Hence, to overcome these obstacles, polysaccharide-based nanohydrogels embedded with natural plant extracts and oils have become the primary choice of pharmaceutical scientists. These gels protect plant-based bioactive compounds and are effective delivery agents because they release multiple bioactive compounds in the targeted area. Nanohydrogels can be applied to infected areas, and due to their contagious nature and penetration power, they get directly absorbed through the skin, quickly reaching the skin's third layer and effectively reducing the fungal infection. In this review, we explain various skin fungal infections, possible treatments, and the effective utilization of plant extract and oil-embedded polysaccharide-based nanohydrogels.

Indexed as

Antifungal AgentsAzolesFungiGelsHumansMicrobial Sensitivity TestsNanostructuresOils, VolatileOnychomycosisPlant ExtractsPlant OilsPolysaccharidesAntifungal AgentsAzolesGelsOils, VolatilePlant ExtractsPlant OilsPolysaccharidesessential oilsfungal infectionsnanohydrogelpolysaccharideskin

Identifiers

PMID34203999
PMCPMC8232670

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.