Evidence map›Paper›PMID 34203982›Full record

ArticleJournal of personalized medicine2021

Severe COVID-19 in Hospitalized Carriers of Single

Margherita Baldassarri, Francesca Fava, Chiara Fallerini, Sergio Daga, Elisa Benetti, Kristina Zguro, Sara Amitrano, Floriana Valentino, Gabriella Doddato, Annarita Giliberti and 16 more

Open access · goldAbstract read
In one paragraph

Article in Journal of personalized medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
4.1field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 31 citations in OpenAlex.

  1. Article
  2. Article
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  4. Article
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  7. Review
  8. Review
  9. Article
  10. Mechanisms by which the cystic fibrosis transmembrane conductance regulator may influence SARS-CoV-2 infection and COVID-19 disease severity.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2023
    Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. The genetic and evolutionary determinants of COVID-19 susceptibility.European journal of human genetics : EJHG · 2022
    Review
  17. Article
  18. Article
  19. Flagellin FromFrontiers in immunology · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

26 authors at 5 institutions in 1 country.

Margherita BaldassarriMedical Genetics, University of Siena, 53100 Siena, Italy.ORCID 0000-0002-0391-1980
Francesca FavaMedical Genetics, University of Siena, 53100 Siena, Italy.ORCID 0000-0002-4363-2353
Chiara FalleriniMedical Genetics, University of Siena, 53100 Siena, Italy.
Sergio DagaMedical Genetics, University of Siena, 53100 Siena, Italy.
Elisa BenettiMed Biotech Hub and Competence Center, Department of Medical Biotechnologies, University of Siena, 53100 Siena, Italy.ORCID 0000-0002-0819-604X
Kristina ZguroMed Biotech Hub and Competence Center, Department of Medical Biotechnologies, University of Siena, 53100 Siena, Italy.
Sara AmitranoGenetica Medica, Azienda Ospedaliero-Universitaria Senese, 53100 Siena, Italy.
Floriana ValentinoMedical Genetics, University of Siena, 53100 Siena, Italy.
Gabriella DoddatoMedical Genetics, University of Siena, 53100 Siena, Italy.
Annarita GilibertiMedical Genetics, University of Siena, 53100 Siena, Italy.
Laura Di SarnoMedical Genetics, University of Siena, 53100 Siena, Italy.
Maria PalmieriMedical Genetics, University of Siena, 53100 Siena, Italy.ORCID 0000-0003-3014-1552
Miriam Lucia CarrieroMedical Genetics, University of Siena, 53100 Siena, Italy.
Diana AlaverdianMedical Genetics, University of Siena, 53100 Siena, Italy.
Giada BeligniMedical Genetics, University of Siena, 53100 Siena, Italy.
Nicola IusoMedical Genetics, University of Siena, 53100 Siena, Italy.
Francesco CastelliDepartment of Infectious and Tropical Diseases, University of Brescia and ASST Spedali Civili Hospital, 25123 Brescia, Italy.ORCID 0000-0001-9161-7804
Eugenia Quiros-RoldanDepartment of Infectious and Tropical Diseases, University of Brescia and ASST Spedali Civili Hospital, 25123 Brescia, Italy.ORCID 0000-0003-1452-9100
Mario Umberto MondelliDepartment of Internal Medicine and Therapeutics, University of Pavia, 27100 Pavia, Italy.
Rosalba MiceliClinical Epidemiology and Trial Organization, Department of Applied Research and Technological Development, Fondazione IRCCS Istituto Nazionale Tumori di Milano, 20133 Milan, Italy.ORCID 0000-0003-0954-375X
Elisa FrullantiMedical Genetics, University of Siena, 53100 Siena, Italy.
Simone FuriniMed Biotech Hub and Competence Center, Department of Medical Biotechnologies, University of Siena, 53100 Siena, Italy.
Francesca MariMedical Genetics, University of Siena, 53100 Siena, Italy.ORCID 0000-0003-1992-1654
Alessandra RenieriMedical Genetics, University of Siena, 53100 Siena, Italy.ORCID 0000-0002-0846-9220
Chiara GabbiIndependent Researcher, 20145 Milan, Italy.ORCID 0000-0002-9764-4771
On Behalf Of The Gen-Covid Multicenter Study
University of Siena · ITUniversity of Brescia · ITAzienda Ospedaliera Universitaria Senese · ITFondazione IRCCS Istituto Nazionale dei Tumori · ITUniversity of Pavia · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The clinical presentation of COVID-19 is extremely heterogeneous, ranging from asymptomatic to severely ill patients. Thus, host genetic factors may be involved in determining disease presentation and progression. Given that carriers of single cystic fibrosis (CF)-causing variants of the

Indexed as

CF carrier screeningCFTRCOVID-19host genetics

Identifiers

PMID34203982
PMCPMC8232773
OpenAlexW3172899954

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.