Evidence map›Paper›PMID 34203967›Full record

ArticleInternational journal of molecular sciences2021

Molecular Inversion Probe-Based Sequencing of

Janine Reurink, Adrian Dockery, Dominika Oziębło, G Jane Farrar, Monika Ołdak, Jacoline B Ten Brink, Arthur A Bergen, Tuula Rinne, Helger G Yntema, Ronald J E Pennings and 10 more

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.6field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 8 citations in OpenAlex.

  1. Trial
  2. Usher Syndrome on the Island of Ireland: A Genotype-Phenotype Review.Investigative ophthalmology & visual science · 2023
    Article
  3. Article
  4. Whole genome sequencing forHGG advances · 2023
    Article
  5. Inherited Retinal Diseases.International journal of molecular sciences · 2022
    Article
  6. Genetic dissection of non-syndromic retinitis pigmentosa.Indian journal of ophthalmology · 2022
    Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors at 6 institutions in 3 countries.

Janine ReurinkDepartment of Human Genetics, Radboud University Medical Center, Geert Grooteplein Zuid 10, 6525 Nijmegen, The Netherlands.ORCID 0000-0002-5677-9258
Adrian DockeryThe School of Genetics & Microbiology, Trinity College Dublin, D02 VF25 Dublin, Ireland.ORCID 0000-0002-3423-2542
Dominika OziębłoDepartment of Genetics, Institute of Physiology and Pathology of Hearing, 02-042 Warsaw/Kajetany, Poland.ORCID 0000-0002-3454-8002
G Jane FarrarThe School of Genetics & Microbiology, Trinity College Dublin, D02 VF25 Dublin, Ireland.ORCID 0000-0002-9959-1992
Monika OłdakDepartment of Genetics, Institute of Physiology and Pathology of Hearing, 02-042 Warsaw/Kajetany, Poland.ORCID 0000-0002-4216-9141
Jacoline B Ten BrinkDepartment of Clinical Genetics, Amsterdam UMC, University of Amsterdam, 1105 Amsterdam, The Netherlands.ORCID 0000-0001-7884-0067
Arthur A BergenDepartment of Clinical Genetics, Amsterdam UMC, University of Amsterdam, 1105 Amsterdam, The Netherlands.ORCID 0000-0002-6333-9576
Tuula RinneDepartment of Human Genetics, Radboud University Medical Center, Geert Grooteplein Zuid 10, 6525 Nijmegen, The Netherlands.ORCID 0000-0003-4350-8106
Helger G YntemaDepartment of Human Genetics, Radboud University Medical Center, Geert Grooteplein Zuid 10, 6525 Nijmegen, The Netherlands.ORCID 0000-0002-3877-6328
Ronald J E PenningsDonders Institute for Brain Cognition and Behaviour, Radboud University Medical Center, 6500 Nijmegen, The Netherlands.ORCID 0000-0001-5517-9683
L Ingeborgh van den BornThe Rotterdam Eye Hospital, 3000 Rotterdam, The Netherlands.ORCID 0000-0002-6375-3339
Marco AbenDepartment of Human Genetics, Radboud University Medical Center, Geert Grooteplein Zuid 10, 6525 Nijmegen, The Netherlands.ORCID 0000-0001-6069-3847
Jaap OostrikDepartment of Otorhinolaryngology, Radboud University Medical Center, 6500 Nijmegen, The Netherlands.ORCID 0000-0002-3980-4220
Hanka VenselaarCentre for Molecular and Biomolecular Informatics, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, 6500 Nijmegen, The Netherlands.ORCID 0000-0001-9824-6559
Astrid S PlompDepartment of Clinical Genetics, Amsterdam UMC, University of Amsterdam, 1105 Amsterdam, The Netherlands.ORCID 0000-0002-4903-8232
M Imran KhanDepartment of Human Genetics, Radboud University Medical Center, Geert Grooteplein Zuid 10, 6525 Nijmegen, The Netherlands.ORCID 0000-0003-0276-5480
Erwin van WijkDonders Institute for Brain Cognition and Behaviour, Radboud University Medical Center, 6500 Nijmegen, The Netherlands.ORCID 0000-0002-5702-3460
Frans P M CremersDepartment of Human Genetics, Radboud University Medical Center, Geert Grooteplein Zuid 10, 6525 Nijmegen, The Netherlands.ORCID 0000-0002-4954-5592
Susanne RoosingDepartment of Human Genetics, Radboud University Medical Center, Geert Grooteplein Zuid 10, 6525 Nijmegen, The Netherlands.ORCID 0000-0001-9038-0067
Hannie KremerDepartment of Human Genetics, Radboud University Medical Center, Geert Grooteplein Zuid 10, 6525 Nijmegen, The Netherlands.ORCID 0000-0002-0841-8693
Radboud University Nijmegen · NLAmsterdam University Medical Centers · NLTrinity College Dublin · IEInstitute of Physiology and Pathology of Hearing · PLMedical University of Warsaw · PLRotterdam Eye Hospital · NL

Funding

Fighting Blindness Ireland FB18CREVelux Stiftung 1129
6 · The paper itself

Abstract

A substantial proportion of subjects with autosomal recessive retinitis pigmentosa (arRP) or Usher syndrome type II (USH2) lacks a genetic diagnosis due to incomplete

Indexed as

Cost-Benefit AnalysisSequence Analysis, DNABase SequenceDNA Copy Number VariationsExonsExtracellular Matrix ProteinsGene DeletionHumansMolecular ProbesPolymorphism, Single NucleotideRetinitis PigmentosaRNA Splice SitesUsher SyndromesExtracellular Matrix ProteinsMolecular ProbesRNA Splice SitesUSH2A protein, humanmolecular inversion probes (MIPs)retinitis pigmentosaUSH2AUsher syndrome type IIa

Identifiers

PMID34203967
PMCPMC8232728
OpenAlexW3169600612

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.