Evidence map›Paper›PMID 34203890›Full record

ArticleCancers2021

NLRP7 Promotes Choriocarcinoma Growth and Progression through the Establishment of an Immunosuppressive Microenvironment.

Deborah Reynaud, Roland Abi Nahed, Nicolas Lemaitre, Pierre-Adrien Bolze, Wael Traboulsi, Frederic Sergent, Christophe Battail, Odile Filhol, Vincent Sapin, Houssine Boufettal and 6 more

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
3.1field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 19 citations in OpenAlex.

  1. Cancers · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 7 institutions in 5 countries.

Deborah ReynaudInstitut National de la Santé et de la Recherche Médicale, Inserm U1292, Université Grenoble-Alpes, 38000 Grenoble, France.ORCID 0000-0002-6968-4215
Roland Abi NahedInstitut National de la Santé et de la Recherche Médicale, Inserm U1292, Université Grenoble-Alpes, 38000 Grenoble, France.ORCID 0000-0002-8767-6462
Nicolas LemaitreInstitut National de la Santé et de la Recherche Médicale, Inserm U1292, Université Grenoble-Alpes, 38000 Grenoble, France.
Pierre-Adrien BolzeDepartment of Gynecological Surgery and Oncology, Obstetrics, French Reference Center for Gestational Trophoblastic Diseases, University Hospital Lyon Sud, University of Lyon 1, 69000 Lyon, France.ORCID 0000-0002-4988-9723
Wael TraboulsiLaboratory for Immuno-Oncology, Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, Washington, DC 2005, USA.
Frederic SergentInstitut National de la Santé et de la Recherche Médicale, Inserm U1292, Université Grenoble-Alpes, 38000 Grenoble, France.
Christophe BattailInstitut National de la Santé et de la Recherche Médicale, Inserm U1292, Université Grenoble-Alpes, 38000 Grenoble, France.ORCID 0000-0001-6849-7824
Odile FilholInstitut National de la Santé et de la Recherche Médicale, Inserm U1292, Université Grenoble-Alpes, 38000 Grenoble, France.ORCID 0000-0003-1964-7958
Vincent SapinGenetics, Reproduction and Development (GReD) Laboratory, CNRS UMR 6293, Inserm U1103, Translational Approach to Epithelial Injury and Repair Team, Clermont Auvergne University, 63000 Clermont-Ferrand, France.ORCID 0000-0002-7452-315X
Houssine BoufettalObstetrics and Gynecology Department, Ibn Rochd University Hospital, Hassan 2 University, Faculty of Medicine and Pharmacy, 20360 Casablanca, Morocco.
Pascale HoffmannInstitut National de la Santé et de la Recherche Médicale, Inserm U1292, Université Grenoble-Alpes, 38000 Grenoble, France.
Touria AboussaouiraObstetrics and Gynecology Department, Ibn Rochd University Hospital, Hassan 2 University, Faculty of Medicine and Pharmacy, 20360 Casablanca, Morocco.
Padma MurthiDepartment of Pharmacology, Monash Biomedicine Discovery Institute, Monash, Clayton, VIC 3168, Australia.ORCID 0000-0003-2535-5134
Rima SlimDepartments of Human Genetics and Obstetrics and Gynecology, McGill University Health Centre Research Institute, Montréal, QC H4A 3J1, Canada.ORCID 0000-0002-4060-2159
Mohamed BenharougaInstitut National de la Santé et de la Recherche Médicale, Inserm U1292, Université Grenoble-Alpes, 38000 Grenoble, France.ORCID 0000-0002-5472-6806
Nadia AlfaidyInstitut National de la Santé et de la Recherche Médicale, Inserm U1292, Université Grenoble-Alpes, 38000 Grenoble, France.ORCID 0000-0002-0718-2447
Inserm · FRUniversity of Hassan II Casablanca · MACentre National de la Recherche Scientifique · FRGeorgetown University · USMcGill University Health Centre · CAThe University of Melbourne · AUUniversité Claude Bernard Lyon 1 · FR

Funding

Agence Nationale de la Recherche 17-EURE-0003Agence Nationale de la Recherche ANR-17-EURE-000FRM SPF20150934074LIGUE SAVOIE 2017
6 · The paper itself

Abstract

The inflammatory gene

Indexed as

choriocarcinomahydatidiform molematernal immune toleranceNLRP7orthotopic model of choriocarcinomatumor microenvironment

Identifiers

PMID34203890
PMCPMC8232770
OpenAlexW3170878484

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.