Evidence map›Paper›PMID 34203803›Full record

ArticleAntioxidants (Basel, Switzerland)2021

The H

Alma Martelli, Eugenia Piragine, Era Gorica, Valentina Citi, Lara Testai, Eleonora Pagnotta, Luca Lazzeri, Nicola Pecchioni, Valerio Ciccone, Rosangela Montanaro and 5 more

Open access · goldAbstract read
In one paragraph

Article in Antioxidants (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
4.2field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 40 citations in OpenAlex.

  1. Article
  2. Glucosinolate Derivatives: Emerging Anti-Inflammatory Agents.Pharmaceuticals (Basel, Switzerland) · 2026
    Review
  3. Article
  4. Naturally Occurring HHandbook of experimental pharmacology · 2026
    Review
  5. Evolution of Secondary Metabolites inFoods (Basel, Switzerland) · 2025
    Article
  6. Transsulfuration Pathway Products and HInternational journal of molecular sciences · 2025
    Review
  7. Epigenetic Mechanisms in Heart Diseases.Reviews in cardiovascular medicine · 2025
    Review
  8. Studying Nitric Oxide in Endothelial Cells.Methods in molecular biology (Clifton, N.J.) · 2025
    Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Plants and Mushrooms as Possible New Sources of HInternational journal of molecular sciences · 2023
    Review
  16. Clinical Potential of Hydrogen Sulfide in Peripheral Arterial Disease.International journal of molecular sciences · 2023
    Review
  17. Article
  18. Anti-Inflammatory Effect of the Natural HInternational journal of molecular sciences · 2022
    Article
  19. Resveratrol-like Compounds as SIRT1 Activators.International journal of molecular sciences · 2022
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 6 institutions in 1 country.

Alma MartelliDepartment of Pharmacy, University of Pisa, Via Bonanno 6, 56126 Pisa, Italy.ORCID 0000-0002-2090-7107
Eugenia PiragineDepartment of Pharmacy, University of Pisa, Via Bonanno 6, 56126 Pisa, Italy.ORCID 0000-0001-6558-3065
Era GoricaDepartment of Pharmacy, University of Pisa, Via Bonanno 6, 56126 Pisa, Italy.
Valentina CitiDepartment of Pharmacy, University of Pisa, Via Bonanno 6, 56126 Pisa, Italy.
Lara TestaiDepartment of Pharmacy, University of Pisa, Via Bonanno 6, 56126 Pisa, Italy.ORCID 0000-0003-2431-6248
Eleonora PagnottaResearch Centre for Cereal and Industrial Crops, CREA Council for Agricultural Research and Economics, Via di Corticella 128, 40134 Bologna, Italy.ORCID 0000-0002-9477-1724
Luca LazzeriResearch Centre for Cereal and Industrial Crops, CREA Council for Agricultural Research and Economics, Via di Corticella 128, 40134 Bologna, Italy.
Nicola PecchioniResearch Centre for Cereal and Industrial Crops, CREA Council for Agricultural Research and Economics, S.S. 673 Km 25,200, 71122 Foggia, Italy.
Valerio CicconeDepartment of Life Sciences, University of Siena, Via A. Moro 2, 53100 Siena, Italy.ORCID 0000-0002-5374-9694
Rosangela MontanaroDepartment of Science, University of Basilicata, Via dell'Ateneo lucano, 10, 85100 Potenza, Italy.
Lorenzo Di Cesare MannelliDepartment of Neuroscience, Psychology, Drug Research and Child Health-NEUROFARBA-Section of Pharmacology and Toxicology, University of Florence, 50139 Florence, Italy.ORCID 0000-0001-8374-4432
Carla GhelardiniDepartment of Neuroscience, Psychology, Drug Research and Child Health-NEUROFARBA-Section of Pharmacology and Toxicology, University of Florence, 50139 Florence, Italy.
Vincenzo BrancaleoneDepartment of Science, University of Basilicata, Via dell'Ateneo lucano, 10, 85100 Potenza, Italy.ORCID 0000-0002-0063-659X
Lucia MorbidelliDepartment of Life Sciences, University of Siena, Via A. Moro 2, 53100 Siena, Italy.ORCID 0000-0001-8148-7049
Vincenzo CalderoneDepartment of Pharmacy, University of Pisa, Via Bonanno 6, 56126 Pisa, Italy.
University of Pisa · ITResearch Centre for Cereal and Industrial Crops · ITUniversity of Basilicata · ITUniversity of Florence · ITUniversity of Siena · ITCereal Research Centre · IT

Funding

CREA Council for Agricultural Research and Economics "Contratto per l'affidamento del servizio di consulenza farmacologica per la caratterizzazione cinetico-chimica del rilascio di acido solfidrico (H2S) da farmaci e molecole di origine naturale in soluzione, in vitro e in vivo e per la valutazione degli efItalian Ministry of Instruction, University and Research (MIUR) PON "Ricerca e Innovazione" 2014-2020-Azione II, by the COMETA research project "Colture autoctone mediterranee e loro valorizzazione con tecnologie avanzate di chimica verde" (Native Mediterranean crops and their enhancement with advanced green chemistryItalian Ministry of University and Research (MIUR) PRIN 2017XP72RF - Hydrogen Sulfide in the Vascular inflamm-Aging: role, therapeutic Oppor-tunities and development of novel pharmacological tools for age-related cardiovascular diseases (SVAgO)University of Pisa, MIUR, Italy "Bando per il finanziamento di Dimostratori Tecnologici DT (DT grant)", acronym "MEDICA"
6 · The paper itself

Abstract

Preservation of vascular wall integrity against degenerative processes associated with ageing, fat-rich diet and metabolic diseases is a timely therapeutical challenge. The loss of endothelial function and integrity leads to cardiovascular diseases and multiorgan inflammation. The protective effects of the H

Indexed as

endothelial permeabilityEruca sativa Mill.erucinH2S-donorhydrogen sulfideisothiocyanatevascular inflammationvascular wall

Identifiers

PMID34203803
PMCPMC8232611
OpenAlexW3171821891

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.