ArticleJournal of clinical medicine2021
Time-Course of Salivary Metabolomic Profiles during Radiation Therapy for Head and Neck Cancer.
Article in Journal of clinical medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed.
- Saliva metabolomics: a non-invasive frontier for diagnosing and managing oral diseases.Journal of translational medicine · 2025Review
- Radiation-induced changes in salivary metabolite profile and pathways in head and neck cancer patients.Clinical oral investigations · 2025Article
- Uracil as a biomarker for spatial pyrimidine metabolism in the development of gingivobuccal oral squamous cell carcinoma.Scientific reports · 2024Article
- Salivary Metabolites Produced by Oral Microbes in Oral Diseases and Oral Squamous Cell Carcinoma: A Review.Metabolites · 2024Review
- Give and Take: The Reciprocal Control of Metabolism and Cell Cycle.Methods in molecular biology (Clifton, N.J.) · 2024Article
- Salivary metabolites as novel independent predictors of radiation pneumonitis.Journal of cancer research and clinical oncology · 2023Article
- Attempts to Understand Oral Mucositis in Head and Neck Cancer Patients through Omics Studies: A Narrative Review.International journal of molecular sciences · 2023Review
- Diagnostic Value of Salivary Amino Acid Levels in Cancer.Metabolites · 2023Review
- Oral Sources of Salivary Metabolites.Metabolites · 2023Review
- Article
- Long-Term Mastication Changed Salivary Metabolomic Profiles.Metabolites · 2022Article
- Salivary Metabolomics for Oral Cancer Detection: A Narrative Review.Metabolites · 2022Review
- Salivary inflammatory mediators as biomarkers for oral mucositis and oral mucosal dryness in cancer patients: A pilot study.PloS one · 2022Article
- Editorial of Special Issue "Metabolomic Analysis in Health and Diseases".Journal of clinical medicine · 2021Article
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Oral mucositis (OM) is one of the most frequently observed adverse oral events in radiation therapy for patients with head and neck cancer. Thus, objective evaluation of OM severity is needed for early and timely intervention. Here, we analyzed the time-course of salivary metabolomic profiles during the radiation therapy. The severity of OM (National Cancer Institute (NCI) Common Terminology Criteria for Adverse Events v3.0) of nine patients with head and neck cancer was evaluated. Partial least squares regression-discriminant analysis, using samples collected before radiation therapy, showed that histidine and tyrosine highly discriminated high-grade OM from low-grade OM before the start of radiation therapy (significant difference,
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.