Evidence map›Paper›PMID 34203691›Full record

ArticleInternational journal of molecular sciences2021

Neuroprotective Metabolites of

Elisa Roda, Erica Cecilia Priori, Daniela Ratto, Fabrizio De Luca, Carmine Di Iorio, Paola Angelone, Carlo Alessandro Locatelli, Anthea Desiderio, Lorenzo Goppa, Elena Savino and 2 more

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 2 pooled it
6.3field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 2 syntheses or guidelines pooled it, 57 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Review
  9. Article
  10. Article
  11. Review
  12. Lion's Mane Mushroom (Nutrients · 2025
    Review
  13. Review
  14. Biofortification of Mushrooms: A Promising Approach.Molecules (Basel, Switzerland) · 2024
    Review
  15. Article
  16. Review
  17. Review
  18. Review
  19. Biology · 2023
    Article
  20. Neurotrophic and Neuroprotective Effects ofInternational journal of molecular sciences · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Elisa RodaLaboratory of Clinical & Experimental Toxicology, Pavia Poison Centre, National Toxicology Information Centre, Toxicology Unit, Istituti Clinici Scientifici Maugeri IRCCS, 27100 Pavia, Italy.
Erica Cecilia PrioriDepartment of Biology and Biotechnology "L. Spallanzani", University of Pavia, 27100 Pavia, Italy.ORCID 0000-0002-2948-2491
Daniela RattoDepartment of Biology and Biotechnology "L. Spallanzani", University of Pavia, 27100 Pavia, Italy.
Fabrizio De LucaDepartment of Biology and Biotechnology "L. Spallanzani", University of Pavia, 27100 Pavia, Italy.ORCID 0000-0002-6462-2373
Carmine Di IorioDepartment of Biology and Biotechnology "L. Spallanzani", University of Pavia, 27100 Pavia, Italy.
Paola AngeloneDepartment of Biology and Biotechnology "L. Spallanzani", University of Pavia, 27100 Pavia, Italy.
Carlo Alessandro LocatelliLaboratory of Clinical & Experimental Toxicology, Pavia Poison Centre, National Toxicology Information Centre, Toxicology Unit, Istituti Clinici Scientifici Maugeri IRCCS, 27100 Pavia, Italy.ORCID 0000-0003-2154-5897
Anthea DesiderioDepartment of Earth and Environmental Science, University of Pavia, 27100 Pavia, Italy.
Lorenzo GoppaDepartment of Earth and Environmental Science, University of Pavia, 27100 Pavia, Italy.
Elena SavinoDepartment of Earth and Environmental Science, University of Pavia, 27100 Pavia, Italy.
Maria Grazia BottoneDepartment of Biology and Biotechnology "L. Spallanzani", University of Pavia, 27100 Pavia, Italy.ORCID 0000-0003-4570-8785
Paola RossiDepartment of Biology and Biotechnology "L. Spallanzani", University of Pavia, 27100 Pavia, Italy.
University of Pavia · ITIstituti Clinici Scientifici Maugeri · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Frailty is a geriatric syndrome associated with both locomotor and cognitive decline, typically linked to chronic systemic inflammation, i.e.,

Indexed as

NeuroprotectionAnimalsCyclooxygenase 2FrailtyGlial Fibrillary Acidic ProteinHealthy AgingHericiumHypoxia-Inducible Factor 1, alpha SubunitInflammationInterleukin-6MaleMiceMice, Inbred C57BLMotor ActivityNitric Oxide Synthase Type IIOxidative StressCyclooxygenase 2Glial Fibrillary Acidic ProteinHif1a protein, mouseHypoxia-Inducible Factor 1, alpha SubunitInterleukin-6Nitric Oxide Synthase Type IIPlant ExtractsSirtuin 1Superoxide Dismutasecerebellumergothioneinefrailtyhealthy agingHericium erinaceusinflammagingneuroprotectionoxidative stress

Identifiers

PMID34203691
PMCPMC8232141
OpenAlexW3171872881

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.