Evidence map›Paper›PMID 34203619›Full record

ArticleJournal of clinical medicine2021

White Spot, a Novel Endoscopic Finding, May Be Associated with Acid-Suppressing Agents and Hypergastrinemia.

Noriko Nishiyama, Hideki Kobara, Maki Ayaki, Shintaro Fujihara, Kaho Nakatani, Naoya Tada, Kazuhiro Koduka, Takanori Matsui, Tadayuki Takata, Taiga Chiyo and 7 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of clinical medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Autoimmune Gastritis: Unveiling the Mystery.The Korean journal of helicobacter and upper gastrointestinal research · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 2 institutions in 1 country.

Noriko NishiyamaDepartment of Gastroenterology, Nishiyama Neurological Hospital, Sakaide City 762-0023, Kagawa, Japan.
Hideki KobaraDepartment of Gastroenterology and Neurology, Faculty of Medicine, Kagawa University, MiKi City 761-0793, Kagawa, Japan.ORCID 0000-0002-8508-827X
Maki AyakiGeneral Medical Center, Department of General Internal Medicine 2, Kawasaki Hospital, Kawasaki Medical School, Okayama City 700-8505, Okayama, Japan.
Shintaro FujiharaDepartment of Gastroenterology and Neurology, Faculty of Medicine, Kagawa University, MiKi City 761-0793, Kagawa, Japan.
Kaho NakataniDepartment of Gastroenterology and Neurology, Faculty of Medicine, Kagawa University, MiKi City 761-0793, Kagawa, Japan.
Naoya TadaDepartment of Gastroenterology and Neurology, Faculty of Medicine, Kagawa University, MiKi City 761-0793, Kagawa, Japan.
Kazuhiro KodukaDepartment of Gastroenterology and Neurology, Faculty of Medicine, Kagawa University, MiKi City 761-0793, Kagawa, Japan.
Takanori MatsuiDepartment of Gastroenterology and Neurology, Faculty of Medicine, Kagawa University, MiKi City 761-0793, Kagawa, Japan.
Tadayuki TakataDepartment of Gastroenterology and Neurology, Faculty of Medicine, Kagawa University, MiKi City 761-0793, Kagawa, Japan.
Taiga ChiyoDepartment of Gastroenterology and Neurology, Faculty of Medicine, Kagawa University, MiKi City 761-0793, Kagawa, Japan.
Nobuya KobayashiDepartment of Gastroenterology and Neurology, Faculty of Medicine, Kagawa University, MiKi City 761-0793, Kagawa, Japan.ORCID 0000-0001-9950-3406
Tingting ShiDepartment of Gastroenterology and Neurology, Faculty of Medicine, Kagawa University, MiKi City 761-0793, Kagawa, Japan.
Koji FujitaDepartment of Gastroenterology and Neurology, Faculty of Medicine, Kagawa University, MiKi City 761-0793, Kagawa, Japan.ORCID 0000-0001-9390-7565
Joji TaniDepartment of Gastroenterology and Neurology, Faculty of Medicine, Kagawa University, MiKi City 761-0793, Kagawa, Japan.ORCID 0000-0001-8801-2505
Tatsuo YachidaDepartment of Gastroenterology and Neurology, Faculty of Medicine, Kagawa University, MiKi City 761-0793, Kagawa, Japan.
Tsutomu MasakiDepartment of Gastroenterology and Neurology, Faculty of Medicine, Kagawa University, MiKi City 761-0793, Kagawa, Japan.
Ken HarumaGeneral Medical Center, Department of General Internal Medicine 2, Kawasaki Hospital, Kawasaki Medical School, Okayama City 700-8505, Okayama, Japan.ORCID 0000-0002-2188-0401
Kagawa University · JPKawasaki Medical School · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

White globe appearance (WGA) is defined as a microendoscopic white lesion with a globular shape underlying the gastric epithelium and is considered a marker of gastric cancer. We recently reported that endoscopically visualized white spot (WS) corresponding to WGA appeared on the nonatrophic mucosa of patients with acid-suppressing agents (A-SA) use. We evaluated patients undergoing routine esophagogastroduodenoscopy and divided the patients into an A-SA group (

Indexed as

acid-suppressing agentantacidsendoscopygastric mucosagastrinemiapotassium-competitive acid blockerproton-pump inhibitorwhite globe appearancewhite spot

Identifiers

PMID34203619
PMCPMC8232144
OpenAlexW3167505474

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.